Conference Object | 2013 | 13TH AFSM PROCEEDINGS , pp.55 - 57
Basvazici-Kulac, B | Ito-Alpturer, M
Conference Object | 2013 | ENVISIONING ARCHITECTURE: DESIGN, EVALUATION, COMMUNICATION , pp.167 - 174
Architectural phenomenology suggests that the basis of perceptual integrity between the subject and a space is multi-sensorial. However, the advancement of visual representation techniques within architecture has led to predominance of the visual experience over other sensory modalities. As a consequence, the integrity of the user's multi-sensorial appreciation of space has been largely neglected which may impact on the holistic experience of the individual. The present study uses an architectural phenomenology approach to explore user experiences of architectural spaces without reference to visual input: the aim being to elucidate . . .key sensory modalities that drive a synthesis of the spatial experience in the absence of visual cues. In this way, the study aims to highlight the role of the non-visual, as a criticism against the tendency to present architecture as a predominantly visual phenomenon. A qualitative study of spatial experiences from four congenitally blind and three late blind individuals was carried out within the framework of architectural phenomenology. Thus, although all suffered total loss of sight, it was possible to assess the impact of latent visual memories within the second group. In-depth interviews with each participant explored responses to four semi-structured, open-ended questions. They were asked to describe; 1) what an architectural space means to them, 2) the place they live, 3) the most important architectural features that affect their experience either positively or negatively and 4) the most favourable and unfavourable place they had ever been. No time limit was imposed for answering the questions. The answers were audio recorded with permission. All participants judged an architectural space predominantly by its acoustic properties, with no clear difference between the congenital or late blindness subgroups. A frequently mentioned construct was the sense of spaciousness with the acoustic properties of architectural features such as materials and ceiling height identified as critical determinants. Tactile experiences, in the form of air circulation felt on the skin also helped the participants to judge spaciousness. But, it was odour that was often described as the feature that defines the identity of a place. Contrary to common beliefs, tactile experiences using the hands were mentioned least. We conclude that non-visual senses subserve a central role in the formulation of spatial experiences for the visually impaired and postulate that they may have similarly significant impact on the experiences of the visually adept. Designing the properties of different acoustical ambiances to promote a synergy of sensory experiences through, for example, the selection of materials or dimensional adjustment at intersections, voids, openings and atria rather than concentrating on visual impact alone would enrich the environmental experience significantly Daha fazlası Daha az
Dinçşahin, Şakir | Arslan, Melis
Article | 2013 | Yakın Doğu Üniversitesi Sosyal Bilimler Dergisi6 ( 2 ) , pp.228 - 250
Hindistan’da ortaya çıkan birbirinden farklı ve hatta birbirine rakip milliyetçilik hareketleri koloni yönetiminden bağımsızlık kazanmak amacıyla işbirliği yaparlar. Ancak bağımsızlık sonrası dönemde milliyetçilik hareketleri arasında rekabet işbirliğinin önüne geçer. Sonuç bölünme, ayrılma, pek çok insanın hayatına mal olan nüfus mübadelesi, otoriter yönetim, dinsel-ulusal elitler arasında siyasal ikileşme, siyasi suikastların iktidar devirme aracı olarak kullanılması ve büyük bir demokrasinin yaşaması için gerekli uzlaşının ortadan kalkması olur. This article illustrates that different and competing nationalist movements were able . . . to join forces for the purpose of achieving self-rule in India in the presence of an external hegemonic force (Britain) controlling politics. However, once independence was accomplished, these competing movements have traded self-rule for self-interest. The result has been secession, threats of secession, mass population exchange at great cost to human life, authoritarian rule, political bifurcation along religio-national nomenclatures, violent transfers of power through assassination, and a general absence of compromise necessary for the successful rule of a large democracy Daha fazlası Daha az
Korachi, M | Ceran, N | Adaleti, R | Nigdelioglu, A | Sokmen, M
Article | 2013 | INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES17 ( 1 ) , pp.228 - 250
Background: Investigational approaches based on genome-wide association studies have proven useful in identifying genetic predictors for many diseases, including susceptibility to chronic hepatitis B and C. In these studies, the majority of genetic variants that have shown a positive association have been identified in genes involved in the immune response. In this study IFN-gamma, IFNGR-1, and IRF-1 genes were analyzed for their role in susceptibility to the development of chronic hepatitis B and chronic hepatitis C in a Turkish population. Methods: Polymorphic genes IRF-1 (-410, -388), IFNGR-1 (-56, -611), and IFN-gamma (+874) wer . . .e analyzed in a total of 400 individuals: 100 chronic hepatitis B patients, 100 hepatitis B carriers, 100 chronic hepatitis C patients, and 100 healthy controls. A single base primer extension assay was used. Correlations between genes and gender, viral load, and aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were also investigated. Results: The IRF-1 gene at positions -388 and -410 were observed to be candidate gene markers for susceptibility to the development of chronic hepatitis B and C (p < 0.05). IFN-gamma +874 and IFNGR-1 (-56 and -611) correlated with chronic hepatitis B but not chronic hepatitis C. Correlation of functional genotype with viral load and AST and ALT levels revealed an association of IFN-gamma +874 and IFNGR-1 -611 with chronic hepatitis C and IFN-gamma +874 with viral load and chronic hepatitis B (p < 0.05). Conclusions: Findings suggest that IFN-gamma (+874), IRF-1 (-410, -388), and IFNGR-1 (-56, -611) are candidate gene markers for determining patient susceptibility to the development of chronic hepatitis B and C. (C) 2012 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved Daha fazlası Daha az
Karamustafalioglu, N. | Kalelioglu, T. | Tanriover, O. | Gungor, F.C. | Genc, A. | Ilnem, C.
Article | 2013 | Psychiatry Investigation10 ( 4 ) , pp.425 - 427
Priapism is defined as having prolonged (more than 6 h), and usually painful penile erection that occurs without a sexual desire or arousal. Only a very few priapism cases caused by ziprasidone are reported in the literature. In this case report we aimed to present a prolonged penile erection due to use of ziprasidone. © 2013 Korean Neuropsychiatric Association.
P. Kizilirmak | M. Berktas | Y. Uresin | O.B. Yildiz
Article | 2013 | Journal of Clinical Hypertension15 ( 3 ) , pp.193 - 200
Many hypertensive patients require ?2 drugs to achieve blood pressure targets. This study aims to review and analyze the clinical studies conducted with dual or triple combination of angiotensin II receptor blockers (ARBs), calcium channel blockers (CCBs), and diuretics. Medical literature between January 1990 and April 2012 was reviewed systematically and data from eligible studies were abstracted. Data were analyzed using random-effects models. Of the 224 studies screened, 7563 eligible patients from 11 studies were included. Triple combinations of ARBs (olmesartan or valsartan), CCBs (amlodipine), and diuretics (hydrochlorothiazi . . .de) at any dose provided more blood pressure reduction in office and 24-hour ambulatory measurements than any dual combination of these molecules ( Daha fazlası Daha az
A Kumar | IA Ince | A Kati | R Chakraborty
Article | 2013 | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY63 , pp.511 - 515
A Gram-positive-staining, rod-shaped, facultatively oligotrophic bacterial strain, designated MB18(T), was isolated from a water sample collected from the River Mahananda at Siliguri (26 degrees 44' 23.20' N, 88 degrees 25' 22.89' a West-Bengal, India. On the basis of 16S rRNA gene sequence similarity, the closest relative of this strain was Brevibacterium epidermidis NCDO 2286(T) (96% similarity). The DNA G+C content of strain MB18(T) was 64.6 molo/o. Chemotaxonomic data [MK-8(H-2) as the major menaquinone, galactose as the sole cell-wall sugar, meso-diaminopimelic acid as the diagnostic cell-wall diamino acid, phosphatidylglycerol . . . and diphosphatidylglycerol as constituents of the polar lipids, anteiso-C-15:0, anteiso-C-17:0 and iso-C-15:0 as the major fatty acids] supported the affiliation of strain MB18T to the genus Brevibacterium. The results of DNA G +C content, 16S rRNA gene sequence analysis and biochemical and physiological analyses allowed genotypic and phenotypic differentiation of strain MB18(T) from its nearest neighbour B. epidermidis. The isolate therefore represents a novel species, for which the name Brevibacterium siliguriense sp. nov. is proposed; the type strain is MB18(T) (=DSM 23676(T)=LMG 25772(T)) Daha fazlası Daha az
A. Kumar | I.A. Ince | A. Kati | R. Chakraborty
Article | 2013 | International Journal of Systematic and Evolutionary Microbiology63 ( PART2 ) , pp.511 - 515
A Gram-positive-staining, rod-shaped, facultatively oligotrophic bacterial strain, designated MB18T, was isolated from a water sample collected from the River Mahananda at Siliguri (26° 44' 23.20' N, 88° 25' 22.89' E), West-Bengal, India. On the basis of 16S rRNA gene sequence similarity, the closest relative of this strain was Brevibacterium epidermidis NCDO 2286T (96% similarity). The DNA G+C content of strain MB18T was 64.6 mol%. Chemotaxonomic data [MK-8(H2) as the major menaquinone, galactose as the sole cell-wall sugar, meso-diaminopimelic acid as the diagnostic cell-wall diamino acid, phosphatidylglycerol and diphosphatidylgl . . .ycerol as constituents of the polar lipids, anteiso-C15: 0, anteiso-C17: 0 and iso-C15: 0 as the major fatty acids] supported the affiliation of strain MB18T to the genus Brevibacterium. The results of DNA G+C content, 16S rRNA gene sequence analysis and biochemical and physiological analyses allowed genotypic and phenotypic differentiation of strain MB18T from its nearest neighbour B. epidermidis. The isolate therefore represents a novel species, for which the name Brevibacterium siliguriense sp. nov. is proposed; the type strain is MB18T (=DSM 23676T=LMG 25772T). © 2013 IUMS Daha fazlası Daha az
Aytekin, O. | Turgut, S. | Üstoglu Ünal, V. | Akşahin, E. | Tomak, M.
Article | 2013 | Physica E: Low-Dimensional Systems and Nanostructures54 , pp.257 - 261
A theoretical study of the effect of the confining potential on the nonlinear optical properties of two dimensional quantum dots is performed. A three-parameter Woods-Saxon potential is used within the density matrix formalism. The control of confinement by three parameters and an applied electric field gives one quite an advantage in studying their effects on the nonlinear properties. The coefficients investigated include the optical rectification, second and third-harmonic generation and the change in the refractive index. Their dependence on the electric field values, dot size and the energy of the incoming photons is studied ext . . .ensively. It is shown that the Woods-Saxon potential can be used to model the confinement in quantum dots with considerable success. © 2013 Elsevier B.V Daha fazlası Daha az
Ince, I.A. | Özcan, K. | Vlak, J.M. | van Oers, M.M.
Article | 2013 | Journal of General Virology94 ( PART11 ) , pp.187 - 192
The temporal expression of the 54 Chilo iridescent virus (CIV) virion protein genes was investigated by combining drug treatments that inhibit protein or DNA synthesis and an RT-PCR strategy particularly suitable for non-polyadenylated mRNAs. This method generates a uniform 3' terminus by ligation of a 5'-phosphorylated oligonucleotide to the 3' end of the transcript that is recognized by a complementary primer during RT-PCR. This analysis showed that CIV virion proteins are encoded by genes in all three predetermined temporal classes: 23 immediate-early, 11 delayed-early and seven late virion gene transcripts were identified and as . . .signed to ORFs. Early transcription of many virion protein genes supports the notion that virion proteins may also play essential roles in the initial stages of infection. In addition, some of the early gene products present in the virion may reflect the intracellular path that the virus follows during infection. © 2013 SGM Daha fazlası Daha az
Celik, H. | Büyükaga, M. | Çelebier, M. | Turkoz Acar, E. | Baymak, M.S. | Gökhan-Kelekçi, N. | Erdogan, H.
Article | 2013 | Journal of Chemical and Engineering Data58 ( 6 ) , pp.1589 - 1596
The acid ionization constant (pKa) values of 2-(3H)-benzoxazolinone and its 17 derivatives were determined in buffered solutions by UV-vis spectrophotometry, potentiometry, and capillary zone electrophoresis techniques. The pKa values of the studied compounds are found to be in the range of 9.01 to 7.15. The advantages and limitations of each technique are discussed. The results suggest that the removal of a proton from the molecule occurred on the nitrogen atom of the 2-(3H)-benzoxazolinone ring and the analgesic/anti-inflammatory activities of the benzoxazolinone derivatives decrease when the pKa values of the compounds increase. . . .© 2013 American Chemical Society Daha fazlası Daha az
Article | 2013 | Annales Mathematiques du Quebec37 ( 2 ) , pp.129 - 172
Let K be a global field. The aim of this speculative paper is to discuss the possibility of constructing the non-abelian version of global class field theory of K by “glueing” the non-abelian local class field theories of K? in the sense of Koch, for each ?? hK, following Chevalley’s philosophy of idèles, and further discuss the relationship of this theory with the global reciprocity principle of Langlands. © 2013, Fondation Carl-Herz and Springer International Publishing Switzerland.