The effects of rhBMP-2 on bone healing in ovariectomized rats treated with zoledronic acid and dexamethasone

Atalay, B. | Cabbar, F. | Guler, N. | Sencift, K.

Article | 2018 | Biomedical Research (India)29 ( 17 ) , pp.3362 - 3369

Background/aim: The aim is to determine the histological findings of recombinant human bone morphogenetic protein-2 (rhBMP-2) on bone healing after zoledronic acid (ZOL) treatment in ovariectomized rats. Materials and methods: The study was performed on 42 female Sprague-Dawley rats untreated for 4 w after ovariectomy. Fourteen rats were injected with 7.5 µg/kg ZOL once a week, and 1 mg/kg dexamethasone per day served as control. Two groups of 14 rats were injected with the same dosage as a control group for once a week for two weeks (group A) and three weeks (group B). The molar teeth in both jaws were extracted two weeks after the . . . first injection for the control group and group A and three weeks for group B. Collagen carriers with rhBMP-2 were implanted into the extraction sockets in groups A and B. The histological findings of new bone formation, and necrotic bone were recorded. Results: The new bone formation was observed in 71.4% of group A and 28.6% of group B (P=0.017). Necrotic bone was observed in 14.3% of both the control group and group A and 71.4% of group B (P=0.032). Conclusion: An increased rhBMP-2 dosage on bone healing after ZOL treatment in ovariectomized rats could lead to new bone formation. © 2018, Scientific Publishers of India. All rights reserved Daha fazlası Daha az

Does giving brief information keep patients calm during different oral surgical procedures?

Cabbar, F. | Burdurlu, M.Ç. | Tomruk, C.Ö.

Article | 2018 | Quintessence International49 ( 10 ) , pp.817 - 828

Objectives: Dental anxiety may play a central role in the oral health status and treatment outcomes of oral surgical procedures. The study aimed to investigate the effect that brief written information has over patients undergoing oral surgical procedures and to evaluate factors that may cause anxiety. Method and Materials: A prospective study was performed on 38 mandibular third molar surgery patients (mean age 26.74 ± 6.44 years) and 56 implant surgery patients (mean age 49.13 ± 15.11 years). Each group was divided into two subgroups, and written information, explaining what they could expect and details about the procedure, was p . . .rovided to study groups. The Spielberger State-Trait Anxiety Inventory was used to measure state (STAI-S) and trait anxiety (STAI-T). The visual analog scale (VAS) was used for pain scores preoperatively and on days 1, 3, 5, and 7. Demographic data and intraoperative behaviors of patients were recorded. Results: All groups had similar anxiety scores at baseline. Preoperative STAI-S and VAS scores were similar between study and control groups (P > .05). Study groups showed significantly lower mean intraoperative anxiety levels (P < .05). The implant group had a significantly lower VAS score (P < .05). STAI-T and preoperative STAI-S were not related to VAS. Postoperative STAI-S and VAS and recuperation were correlated (P < .05). Women showed significantly higher anxiety and VAS scores. Conclusion: The patients who received written information did not report lower anxiety scores. However, improved patient cooperation could be achieved with this method. Different surgical procedures may cause anxiety for different reasons. © 2018 Quintessenz Daha fazlası Daha az

Implant stability outcomes after immediate and delayed revascularized free fibula flaps: A preliminary comparative study

Cabbar, F. | Kocaaslan, F.N.D. | Saçak, B. | Çapar, G.D. | Çelebiler, Ö.

Article | 2018 | International Journal of Oral and Maxillofacial Implants33 ( 6 ) , pp.1368 - 1373

Purpose: This pilot study investigated the retrospective outcomes of implants placed immediately or with a delayed protocol in revascularized free fibula flaps (FFF). Materials and Methods: Patients undergoing FFF between 2014 and 2017 were included in the study. Implants were inserted either immediately or 23.63 ± 10.61 months after reconstructive surgery. Resonance frequency analyses were recorded at the time of implant placement (first control) and 4 months postoperatively while uncovering and screwing the gingiva formers (second control). The statistical significance level was set at P < .05. Results: Eight patients (four men, f . . .our women, mean age: 46.75 ± 12.96 years) were included in the study. Twenty-six implants were placed in FFF (14 immediate, 12 delayed), and 28 were placed in the alveolus. All implant stability quotient (ISQ) scores were in high stability ranges. Statistically significant differences were observed between delayed (79.25 ± 4.77) and immediate implant placement (73.14 ± 7.42) at first controls, but not at second controls (79.17 ± 3.59 and 76.00 ± 6.18). The ISQ values of immediate implant placement significantly increased from first to second controls (P = .018). Bicortically placed implants showed significantly higher scores than unicortical implants (P < .05). ISQ values of FFF and alveolar bone groups were similar (P > .05). Conclusion: High stability scores similar to alveolar bone could be achieved by both immediate and delayed implant placement. Bicortical implantation results in better implant stability. ©2018 by Quintessence Publishing Co Inc Daha fazlası Daha az

What is the survival rate of dental implants in Turkey? A systematic review

Cabbar, F. | Burdurlu, M.Ç. | Işiksaçan, N.S. | Atalay, B. | Çapar, G.D.

Review | 2018 | Biomedical Research (India)29 ( 3 ) , pp.485 - 495

Objectives: The purpose of this study was to examine the failures of dental implants in Turkey and to investigate the complications, which may lead to implant loss. Study Design: The Systematic review was performed in accordance with PRISMA statement and Cochrane guidelines. PubMed, Google Scholar, Cochrane Library, TUBITAK ULAKBIM databases were searched for both in English and Turkish up to 2015. Data on implant failure, demographic variables and outcomes were included. Nonclinical and animal reports were excluded. Search was conducted by two authors and conflicts were resolved by a third reader. Results: Seventeen reports were sa . . .tisfied the inclusion criteria. In total, 1764 (51.19% female and 48.81% male) participants were included. A total of 4487 implants were used. Total implant success was 97.48% (61 early and 52 late failures) in a follow-up period for 42.71 ± 33.78 months. The failure reasons were infection (38.9%), lack of osseointegration (44.4%), implant fractures (5.8%), periimplantitis (1.76%), sensory disturbances (2.65%). Conclusion: Immediate and late implantation has similar failure rates and failure rates may increase with time. Implants have similar survival rates with the literature in Turkey region as well. It was observed that few reports with limited data were reported considering the high number of implants placed in the Turkey. © 2018, Scientific Publishers of India. All rights reserved Daha fazlası Daha az

Evaluation of significant radiographic findings and their impact on the oral health-related quality of life of patients with complete dentures

Cabbar, F. | Burdurlu, M.Ç. | Çapar, G.D. | Tekin, H. | Tomruk, C.Ö.

Article | 2018 | International Journal of Prosthodontics31 ( 6 ) , pp.594 - 600

Purpose: The aim of this study was to assess the frequency and location of positive radiographic findings in edentulous patients and to evaluate the oral health-related quality of life (OHRQoL) and complacency of patients with positive radiologic findings. Materials and Methods: A total of 1,349 asymptomatic edentulous patients were retrospectively evaluated using a digital panoramic system for the presence of retained root fragments, impacted teeth, foreign bodies, radiolucencies, radiopacities, mental foramen at or near the alveolar crest, and maxillary sinus pneumatization. The patients with positive findings were called for a fo . . .llow-up to take a new panoramic radiograph. The functional status and symptoms of participants were measured with the Oral Health Impact Profile (OHIP-14). Results: At least one or more of the radiographic findings were observed in 35.21% of the evaluated radiographs. The most frequent finding was sinus pneumatization (20.9%). The mean total OHIP score was 9.74 ± 8.34. There was no statistically significant difference observed for gender, age, education levels, marital status, or having surgical interventions for total OHIP- 14 scores (P >.05). Conclusion: The results of this study suggest that routine radiographic examination of edentulous patients may not be crucial before rehabilitation, and using a total percentage of positive radiographic findings may result in the exaggeration of the disease risk in edentulous patients. © 2018 by Quintessence Publishing Co Inc Daha fazlası Daha az

6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

Bu site altında yer alan tüm kaynaklar Creative Commons Alıntı-GayriTicari-Türetilemez 4.0 Uluslararası Lisansı ile lisanslanmıştır.