Diffusion-weighted imaging of the renal and adrenal lesions

Kilickesmez, O. | Inci, E. | Atilla, S. | Tasdelen, N. | Yetimoglu, B. | Yencilek, F. | Gurmen, N.

Article | 2009 | Journal of Computer Assisted Tomography33 ( 6 ) , pp.828 - 833

Objectives: The purpose of this study was to calculate the apparent diffusion coefficient (ADC) values of different renal and adrenal lesions to evaluate the ability of diffusion-weighted imaging in characterizing masses and determining malignancy. Methods: A total of 52 patients consisting of 67 renal lesions and 28 patients with 33 adrenal lesions in addition to 50 healthy controls with normal kidneys were enrolled in the study. Diffusion-weighted imaging was performed with b factors of 0, 500, and 1000 s/mm, and the ADCs of the normal kidney and renal and adrenal lesions were calculated. Results: The mean (SD) ADCs of the renal c . . .ortex and medulla of the control group were 2.08 (0.22) × 10 and 1.94 (0.18) × 10 mm/s, respectively. Focal renal lesions were as follows: simple cysts (2.94 [0.20] × 10 mm/s), hemorrhagic cysts (1.71 [0.38] × 10 mm/s), angiomyolipomas (1.40 [0.21] × 10 mm/s), renal cell carcinomas (1.06 [0.39] × 10 mm/s), metastases (1.50 [0.13] × 10 mm/s), and hydronephrosis (1.54 [0.25] × 10 mm/s). The mean ADCs of all these pathologies were significantly different when compared with normal parenchyma. Diffusion-weighted imaging was also able to differentiate angiomyolipomas and hemorrhagic cysts from renal cell carcinomas. Adrenal lesions were subgrouped as adenomas (1.41 [0.27] × M10 mm/s), nonadenomatous solid masses (1.08 [0.28] × 10 mm/s), and cysts (2.82 [0.24] × 10 mm/s). The mean ADCs of adenomas were significantly different when compared with nonadenomatous solid masses and cysts. Conclusions: Our findings show that ADC measurement has a potential ability to differentiate benign and malignant focal renal and adrenal lesions with the guidance of conventional sequences. When used alone, diffusion-weighted imaging may lead to misdiagnoses due to overlapping ADCs of the lesions. Copyright © 2009 by Lippincott Williams & Wilkins Daha fazlası Daha az

The evaluation of saphenofemoral insufficiency in primary adult varicocele

Koyuncu, H. | Ergenoglu, M. | Yencilek, F. | Gulcan, N. | Tasdelen, N. | Yencilek, E. | Sarica, K.

Article | 2011 | Journal of Andrology32 ( 2 ) , pp.151 - 154

The aim of this study was to evaluate the possible relationship between varicocele and saphenofemoral insufficiency in patients diagnosed with primary varicocele. A total of 70 patients with the primary diagnosis of varicocele were included into the study. A total of 30 age-matched healthy adults were also included in the study as a control group. Varicocele was diagnosed by palpation and observation of each spermatic cord in standing position before and during a valsalva maneuver. Additionally, scrotal Doppler and lower extremity venous Doppler ultrasonography were performed. Patients who were with spermatic varicose vein larger th . . .an 3.0 mm were included in the study group as a varicocele patient. At the lower extremity venous Doppler ultrasonography, a retrograde flow lasting longer than 0.5 seconds during normal breathing or at the valsalva maneuver was considered to be meaningful for saphenofemoral junction insufficiency. Thirty-six (51.35%) patients had insufficiency in saphenofemoral junction in the study group (6 [8.5%] bilateral, 30 [42.85%] unilateral) whereas 8 (26.6%) had insufficiency in the control group (2 [6.6%] bilateral, 6 [20%] unilateral insufficiency). The patients with primary varicocele had a statistically significant (P 5 .02) higher rate of venous insufficiency in their saphenofemoral junctions when compared with the control group. In the present study, the rate of saphenofemoral insufficiency has been found to be statistically higher in patients with primary varicocele compared with healthy men. Depending on the common presence of valvular insufficiency, we believe that the presence of varicocele should be investigated in the young population suffering from saphenofemoral junction insufficiency Daha fazlası Daha az

Diagnostic utility of DTI in prostate cancer

Gürses, B. | Tasdelen, N. | Yencilek, F. | Kilickesmez, N.O. | Alp, T. | Firat, Z. | Gürmen, A.N.

Article | 2011 | European Journal of Radiology79 ( 2 ) , pp.172 - 176

Purpose: The aim of this study was to compare the diffusion tensor parameters of prostate cancer, prostatitis and normal prostate tissue. Materials and Methods: A total of 25 patients with the suspicion of prostate cancer were included in the study. MRI was performed with 3 T system (Intera Achieva, Philips Medical Systems, The Netherlands). T2 TSE and DTI with ss-EPI were obtained in each subject. TRUS-guided prostate biopsy was performed after the MRI examination. Images were analyzed by two radiologists using a special software system. ROI's were drawn according to biopsy zones which are apex, midgland, base and central zone on e . . .ach sides of the gland. FA and ADC values in areas of cancer, chronic prostatitis and normal prostate tissue were compared using Student's t-test. Results: Histopathological analysis revealed carcinoma in 68, chronic prostatitis in 67 and was reported as normal in 65 zones. The mean FA of cancerous tissue was significantly higher (p < 0.01) than the FA of chronic prostatitis and normal gland. The mean ADC of cancerous tissue was found to be significantly lower (p < 0.01), compared with non-cancerous tissue. Conclusion: Decreased ADC and increased FA are compatible with the hypercellular nature of prostate tumors. These differences may increase the accuracy of MRI in the detection of carcinoma and to differentiate between cancer and prostatitis. © 2010 Elsevier Ireland Ltd Daha fazlası Daha az

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