Özdurak, C. | Ulusoy, V.

Article | 2012 | European Journal of Economics, Finance and Administrative Sciences ( 52 ) , pp.80 - 85

The aim of this paper is to add to the literature on volatility forecasting using data from the Istanbul stock market to determine if the real estate investment trusts (REITs) return responses to variance differ from ISE 100 Price Index. The main reason choosing REITs as the subject of our paper is the usage of them as an interest rate hedge instrument in recent years. Moreover since in the literature it is represented that REITs' merger and acquisitions in stock market development have positive impact on REITs investment we included Saf GYO in our anlysis because of the Saglam İnşaat and Saf GYO merger and acquisitions on November . . .2011. As of 31.12.2011 Saf GYO comprises 9,6% of XGMYO Index companies total asset sum. In this context we concluded that XGMYO return and variance relationship differ from ISE 100 Price Index and Saf GYO. The new effect and shocks have more impact on XGMYO returns compared to Saf GYO and ISE 100 Price Index. Finally we presented the result of the models as XGMYO returns and benchmark interest rates have a strong positive relationship which indicates that it will be relevant to use REITs as an interest rate hedge instrument. © EuroJournals, Inc. 2012 Daha fazlası Daha az

Yılmaz, B. | Sandal, S. | Ayvaci, H. | Tug, N. | Vitrinel, A.

Article | 2012 | Mutation Research - Genetic Toxicology and Environmental Mutagenesis749 ( 01.02.2020 ) , pp.17 - 22

We have investigated the presence of DNA damage in human mammary epithelial cells collected from healthy lactating mothers (age, 20-35 years) who were resident in the Istanbul area. Breast milk (10. ml) was collected from 30 women between one and two weeks post-. partum. Demographic information (parity, breast cancer, occupation, duration of residency in Istanbul, consumption of fish, beef and poultry) was also obtained. Milk samples were diluted 1:1 with RPMI 1640 medium and centrifuged to collect cells. The cells were re-suspended and cell viability was determined by use of 0.4% trypan blue. DNA damage was assessed by use of the c . . .omet assay (alkaline single-cell gel electrophoresis). Fifty cells per slide and two slides per sample were scored to evaluate DNA damage. The cells were visually classified into four categories on the basis of extent of migration: undamaged (UD), lightly damaged (LD), moderately damaged (MD) and highly damaged (HD). Total comet scores (TCS) were calculated as: 1× UD. +. 2× LD. +. 3× MD. +. 4× HD. Exfoliated mammary cells of the donors showed high (TCS. ? 150. a.u.), moderate and low DNA damage in 10 (33.3%), 8 (26.7%) and 12 (40%) mothers, respectively. There was no significant correlation between TCS for DNA damage and the duration of previous breastfeeding, parity or age. None of the mothers was vegetarian, smoker or on any medication. Meat and chicken consumption did not significantly correlate with the TCS values. Fish consumption was significantly correlated with TCS results (Spearman's rho = 0.39, Daha fazlası Daha az

Ataman, AD | Vatanoglu-Lutz, EE

Article | 2012 | JOURNAL OF NEUROLOGICAL SCIENCES-TURKISH29 ( 4 ) , pp.895 - 899

During the times of World War I, Germany was an important pioneer in many areas of science and medicine. Alois Alzheimer, who lived during this period, was one of the founders of the field of neuropathology. He described a form of dementia as a brain destroying disease more than 100 years ago. This paper provides an overview on the discovery of the Alzheimer disease and the physician behind this discovery, Alois Alzheimer, through philately.

Monkul, M.M.

Conference Object | 2012 | Geotechnical Special Publication ( 225 GSP ) , pp.799 - 808

Silty sands are among the soil types that are prone to liquefaction when subjected to static or dynamic undrained loading. Today, it is widely accepted that clean sands and silty sands react differently in terms of liquefaction behavior. With this observation, factors influencing fines' role on such a difference have been investigated by various researchers. Some of those factors such as laboratory specimen preparation method and confining stress are relatively well understood. However, some others such as fines content (FC) are still debated and being investigated. More explicitly, there is not a widely accepted consensus on whethe . . .r increasing fines content increases or decreases the liquefaction resistance of silty sands, even with the same comparison basis (i.e. loosest possible density after deposition, same void ratio, same relative density etc.). Recently, relative size of silt grains to the sand grains is also found to be another factor influencing the fines' role on liquefaction behavior of silty sands. In this paper, some of the research in literature regarding liquefaction of silty sands is re-visited and various factors influencing the fines' role on liquefaction behavior are summarized. © 2012 American Society of Civil Engineers Daha fazlası Daha az

Salmanoglu, M. | Kucukardali, Y. | Kucukodaci, Z. | Fenercioglu, A. | Solmazgul, E. | Onem, Y. | Ozata, M.

Article | 2012 | Journal of Endocrinological Investigation35 ( 4 ) , pp.401 - 406

https://hdl.handle.net/20.500.11831/767

Işeri, U. | Özkurt, Z. | Yalniz, A. | Kazazoglu, E.

Article | 2012 | Journal of Prosthetic Dentistry107 ( 5 ) , pp.309 - 315

Statement of problem: The surface of zirconia ceramic is damaged during grinding, which may affect the mechanical properties of the material. Purpose: The purpose of this study was to compare the biaxial flexural strength of zirconia after different grinding procedures and to measure the temperature rise from grinding. Material and methods: Forty disk-shaped zirconia specimens (15 × 1.2 mm) with a smaller disk in the center of each disk (1 × 3 mm) were divided into 4 groups (n=10). The specimens were ground with a high-speed handpiece and micromotor with 2 different grinding protocols, continual grinding and periodic grinding (10 se . . .conds grinding with 10 seconds duration), until the smaller disk was removed. Control specimens without the center disk (n=10) were analyzed without grinding. The biaxial flexural strengths of the disks were determined in a universal testing machine at a crosshead speed of 0.5 mm/min. The fracture strength (MPa) was recorded, and the results were analyzed using a 1-way ANOVA, Tukey HSD test, Student's t test, and Pearson correlation test (?=05). Results: All grinding procedures significantly decreased flexural strength ( Daha fazlası Daha az

Aydogan, H.Y. | Küçükhüseyin, Ö. | Tekeli, A. | Lsbir, T.

Article | 2012 | Genetic Testing and Molecular Biomarkers16 ( 2 ) , pp.134 - 137

Aim: The aim of the present study was to investigate the individual and combined effects of receptor for advanced glycation end products (RAGE) -374T/A, RAGE Gly82Ser, and peroxisome proliferator-activated receptor gamma (PPAR-?) Pro12Ala polymorphisms on the development of coronary artery disease (CAD). Materials and Methods: This study was carried out in 87 patients with CAD and 52 CAD-free healthy controls. Polymerase chain reaction, restriction fragment length polymorphism, and agarose gel electrophoresis techniques were used to determine RAGE -374T/A, RAGE Gly82 Ser, and PPAR-? Pro12 Ala. Results: Individual allele and genotype . . . frequencies of RAGE -374T/A, RAGE Gly82Ser, and PPAR-? Pro12Ala polymorphisms were not significantly different between study groups. However, compared with the control group, wild-type T allele frequency was found to be higher in patients with diabetes (p=0.009). To investigate the combined effects of RAGE and PPAR polymorphisms, haplotype analysis was elevated and there was no statistical difference between the haplotypes of RAGE Gly82Ser with RAGE-374T/A or PPAR Pro12Ala. However, the frequency of RAGE-374T/PPAR12Ala haplotype was found to be higher in both the patient group (p=0.024) and in patients without diabetes (p=0.037). Conclusion: The results of the present study demonstrated that possessing the A allele of RAGE -374T/A polymorphism by diabetic CAD patients and possessing the-374T/Ala12 haplotype of RAGE -374T/A and PPAR-? Pro12 Ala polymorphisms by the patients group were the most important risk factors for CAD. © Copyright 2012, Mary Ann Liebert, Inc. 2012 Daha fazlası Daha az

Eren, Z. | Çoban, J. | Ekinci, I.D. | Kaspar, C. | Kantarci, G.

Article | 2012 | Advances in Clinical and Experimental Medicine21 ( 3 ) , pp.321 - 329

Background. Endotoxins can cause serious organ damage and death by triggering the secretion of pro-inflammatory cytokines such as TNF-?, IL-6 and IL-Iß in bacterial infections. Objectives. The goal of this study was to evaluate the effects of a high dose (3000 U/kg) of erythropoietin-beta (EPO) on inflammatory cytokine levels, renal function and histological changes during the early period of Lipopolysaccharide (LPS)-induced endotoxemia using a rat model. Material and Methods. Male Sprague Dawley (350-400 g) rats were randomized into 3 groups: Control group (n = 7); LPS group (received 20 mcg/kg LPS through intraperitoneal (i.p.) in . . .jection (n = 7); LPS+EPO group (received 3000 U/kg, ip 30 minutes before LPS administration (n = 7). Four hours after the administration of LPS, kidney tissue and serum samples were collected. Kidney function parameters, TNF-?, IL-6, IL-1ß, C reactive protein (CRP) and complete blood counts (CBC) were measured. The severity of renal tubular injury and caspase-9 immunoreactive cells was expressed as a percentage. Results. Serum levels of urea, creatinine, TNF-?, IL-6 and IL-1ß were significantly increased in the LPS group (p < 0.0001 - p = 0.04) and were lower in LPS+EPO group (p < 0.0001, p = 0.01, p = 0.02, p = 01 and p < 0.0001, respectively). Pretreatment with EPO significantly increased platelet counts (p = 0.00) and decreased white blood cell counts (p = 0.02). The renal tubular injury percentage was significantly higher in the LPS group than in the control and LPS+EPO groups (p = 0.002, p = 0.003, and p = 0.005, respectively) and caspase-9 expression was lower in the LPS+EPO and control groups than in the LPS group. Conclusions. EPO might have renoprotective effects against the inflammatory process and cell apoptosis during endotoxemia. © Copyright by Wroclaw Medical University Daha fazlası Daha az

Ozcan, E | Aydin, K | Baser, GM | Guclu-Ustundag, O | Korachi, M | Ekinci, FY

Conference Object | 2012 | NEW BIOTECHNOLOGY29 , pp.321 - 329

…

Api, M. | Api, O.

Article | 2012 | Journal of the Pakistan Medical Association62 ( 3 ) , pp.284 - 286

Endometrial ablation is one of the most effective methods for treatment of dysfunctional uterine bleeding (DUB). Balloon devices with circulating hot water inside or electrodes on the outer surface and radiofrequency-induced thermal destructors are the most recently introduced available tools for endometrial ablation. All of these methods are effective and simple but expensive technologies. The aim of this brief report is to evaluate the effectiveness and safety of a new, simple and money-saving procedure, namely foley catheter balloon endometrial ablation (FCBEA), for treatment of DUB. We present our experience with FCBEA performed . . . on 3 women with severe meno-metrorrhagia unresponsive to medical therapy. There were no procedurerelated complications with achievement of complete amenorrhea for a 19 months follow-up period. Although FCBA has yielded encouraging results, there exists a need for further investigation and validation on larger groups, before its universal application Daha fazlası Daha az

Özcan, E. | Parkes, A.J. | Alkan, A.

Article | 2012 | Computers and Operations Research39 ( 10 ) , pp.2310 - 2322

Timetabling problems are well known NP-hard constraint satisfaction problems, and real-world cases often have complicated and challenging structures. For such problems, we present a new hybrid method, Interleaved Constructive Memetic Algorithm (ICMA) that interleaves memetic algorithms with constructive methods. ICMA works using an active subset of all the events. Starting with a few events, in multiple construction stages ICMA increases the active set to eventually include all of them. At each stage, a memetic algorithm (MA) is applied to improve the current partial solution before the next construction step. We also describe a rea . . .l-world course timetabling problem, the Preparation School Timetabling Problem (PSTP), which is of particular interest because it has a highly hierarchical structure arising from various organisational requirements. An important advantage of ICMA is that both the constructive heuristics and MA can be tailored to exploit such hierarchical structures. We give empirical results showing that ICMA performs better than the corresponding conventional MA on the PSTP. © 2011 Elsevier Ltd. All rights reserved Daha fazlası Daha az

Tozlu, M. | Oztoprak, M.O. | Arun, T.

Article | 2012 | Lasers in Medical Science27 ( 6 ) , pp.1151 - 1155

Laser use is effective in the debonding of ceramic brackets. However, a standardization of the laser debonding techniques used has not yet been implemented. The purpose of this study was to evaluate the effect of the time lag elapsed between lasing and shearing on debonding of ceramic brackets. One hundred polycrystalline ceramic brackets were placed on human premolar teeth, which were randomly divided into five groups of 20. One group was assigned as the control. The Er-YAG laser was applied on each bracket in four experimental groups at 5 W for 6 s with the scanning method. Debonding was performed 1 s, 18 s, 30 s, or 60 s after la . . .ser exposure. Shear bond strengths and adhesive remnant index scores were measured. Statistically significant difference was observed between the control and experimental groups when the data for the shear bond strengths was considered (p < 0.05). Adhesive remnant index scores of the groups were not statistically different (p > 0.05). Debonding ceramic brackets after 18 s when lased 6 s using an Er-YAG laser with the scanning method is safe and also suitable for clinical use since three brackets can be debonded at a time in succession. © 2011 Springer-Verlag London Ltd Daha fazlası Daha az