Gürbüz, C. | Öztürk, M.I. | Koca, O. | Yildirim, A. | Ateş, F. | Eryildirim, B. | Sarica, K.

Article | 2011 | Turk Uroloji Dergisi37 ( 3 ) , pp.252 - 256

Objective: In this study, the adequacy of technical equipment used in the treatment of renal stone along with treatment approaches was evaluated. Materials and methods: Between January 2010 and June 2010, 106 urology residents and specialists practicing in 10 different urology departments of training hospitals in İstanbul were asked to fill a questionnaire to evaluate the adequacy of necessary equipment and the treatment approaches for the treatment of renal stone. Results: Eighty percent of the physicians who participated in the study treated at least 8 patients with renal stone per month. While all participating clinics had rigid . . .nephro-scope, flexible ureterorenoscopy and electroshock wave lithotriptor were available in 41% and 49% of the clinics, respectively. The preferred radiologic evaluation before percutaneous nephrolithotomy (PNL) was intravenous pyelography, and abdominopelvic computed tomography in 72% and 69%, respectively. Tubeless PNL was not preferred by 71% of the participants. The first choice of treatment for coraliform stone was PNL and open surgery in 71% and 26% of participants, respectively. Fifty-four percent of the participants stated that PNL was applied for patients older than 12 years old. Retrograde intrarenal surgery was suggested by 26% of the participants for the treatment of symptomatic lower calix stone. Conclusion: It is encouraging that PNL application is performed in all clinics involved in this study, however, training hospitals should be more equipped Daha fazlası Daha az

Koyuncu, H. | Yencilek, F. | Erturhan, S. | Eryildirım, B. | Sarica, K.

Article | 2011 | International Urology and Nephrology43 ( 1 ) , pp.7 - 13

Objective: To evaluate the natural course of the stone disease in pediatric patients from different perspectives among which the spontaneous passage and stone recurrence rates evaluated during the follow-up. Materials and methods: A total of 142 children referring with primary urinary stone disease were evaluated and followed. All children in the study were divided into two groups with respect to the age (Group 1: 0-5 years and Group 2: 6-15 years). Children were followed with respect to spontaneous passage rates, recurrence-regrowth rates, physical as well as the renal growth rates. Results: Stone recurrence has been noted in 44% o . . .f patients in group 1, this value was 31% in group 2. Children with at least one identifiable metabolic abnormality tended to have higher recurrence rates than the others despite conservative measures. The average stone recurrence rate in children without any metabolic abnormality was 14% and nearly 50% in children with an identifiable metabolic abnormality. Conclusions: We may emphasize that due to the high recurrence and re-growth rates, all children with urinary stone disease should be followed closely with regular visits. The evaluation of metabolic risk factors in children with renal stone disease is the basis of medical treatment aimed at preventing recurrent stone events and the growth of pre-existing calculi. © 2010 Springer Science+Business Media, B.V Daha fazlası Daha az

Yencilek, F. | Erturhan, S. | Cangüven, Ö. | Erol, B. | Koyuncu, H. | Göktaş, C. | Sarica, K.

Article | 2009 | Turk Uroloji Dergisi35 ( 4 ) , pp.298 - 303

Objective: The aim of this study was to determine the effect of indomethacin, an anti-inflammatory agent, on apoptosis and crystal deposition developing as a consequence of tubular cell injury induced by hyperoxaluria in an animal model. Materials and methods: Fifty New Zealand rabbits were divided into 3 groups. The first 2 groups were fed with hyperoxaluric diet and Group 3 was the control group with no supplementary procedure or treatment. While the animals in Group 1 were given only hyperoxaluric diet, Group 2 animals was applied indomethacin in addition to the hyperoxaluric diet. Animals were sacrificed at the early (7th day) a . . .nd late (28th day) periods and renal tis-sue specimens were sent for the pathological analysis of crystal deposition and apoptosis. Results: The presence and degree of crystal deposition were significantly less in the specimens obtained from indomethacin-treated group during both the early and late periods ( Daha fazlası Daha az

Aydin, H. | Yencilek, F. | Erihan, I.B. | Okan, B. | Sarica, K.

Article | 2011 | Urological Research39 ( 6 ) , pp.451 - 458

Both the prevalence of cardiovascular risk factors and event rate are increased in patients with urolithiasis. Screening is recommended to all patients who have high cardiovascular risk. The aim of this study was to document 10-year risk of cardiovascular disease and mortality in asymptomatic patients with urolithiasis. Consecutive 200 patients with calcium oxalate urolithiasis were compared with 200 age- and sex-matched healthy controls. Ten-year cardiovascular disease risk was calculated with the Framingham Risk Score and mortality risk with SCORE risk score. Calcium, oxalate, and citrate excretion were studied as urinary stone ri . . .sk factors. The results indicate that patients with urolithiasis had higher total cholesterol (p < 0.0001), lower HDL-cholesterol (p < 0.0001), and higher systolic blood pressure (p < 0.0001) and hsCRP (p < 0.0001) compared with controls. Patients with urolithiasis had a higher Framingham Risk Scores [OR 8.36 (95% CI 3.81-18.65), p = 0.0001] and SCORE risk score [OR 3.02 (95% CI 1.30-7.02), p = 0.0006] compared with controls. The Framingham and SCORE risk score were significantly correlated with urinary calcium (p = 0.0001, r = 0.460, and p = 0.005, r = 0.223, respectively) and oxalate excretion (p = 0.0001, r = 0.516, p = 0.001, r = 0.290, respectively). In multiple linear regression analysis, urinary calcium and oxalate excretion, age, sex, total cholesterol, HDL-cholesterol, hsCRP and smoking were the independent predictors of 10-year cardiovascular disease risk and urinary calcium and oxalate excretion, age, sex, total cholesterol, fasting blood glucose for 10-year cardiovascular mortality. In conclusion, patients with calcium oxalate urolithiasis carry high risk of cardiovascular disease and mortality. All patients should be screened at the initial diagnosis of urolithiasis for the risk factors. © 2011 Springer-Verlag Daha fazlası Daha az

Yencilck, F. | Aktas, C. | Goktas, C. | Yilmaz, C. | Yilmaz, U. | Sarica, K.

Article | 2008 | International Braz J Urol34 ( 6 ) , pp.786 - 787

[No abstract available]

Sarica, K.

Article | 2009 | European Urological Review4 ( 2 ) , pp.83 - 86

Management of paediatric urinary stones is still a challenge. The desired outcome is complete clearance of stones, preservation of renal function and prevention of stone recurrence. Improvements in technology and growing experience have resulted in greater acceptance of minimally invasive techniques, and currently urologists can use the whole spectrum of stone management alternatives in children as well as in adults. Shock-wave lithotripsy (SWL) is the first choice for upper tract calculi, while other minimally invasive methods have more specific indications. Although SWL is safe and efficient in the treatment of both renal and uret . . .eral stones, ureteroscopy and percutaneous nephrolithotomy (PCNL), in expert hands, can be successfully applied in appropriate cases. With judicious application of these treatment modalities, excellent stone-free rates with minimal morbidity can be obtained. In patients with anatomical abnormalities, open surgery is preferred. Stone-related factors, collecting system anatomy, presence of obstruction and/or infection of the urinary tract should be considered in all cases. © Touch Briefings 2009 Daha fazlası Daha az

Koyuncu, H. | Ergenoglu, M. | Yencilek, F. | Gulcan, N. | Tasdelen, N. | Yencilek, E. | Sarica, K.

Article | 2011 | Journal of Andrology32 ( 2 ) , pp.151 - 154

The aim of this study was to evaluate the possible relationship between varicocele and saphenofemoral insufficiency in patients diagnosed with primary varicocele. A total of 70 patients with the primary diagnosis of varicocele were included into the study. A total of 30 age-matched healthy adults were also included in the study as a control group. Varicocele was diagnosed by palpation and observation of each spermatic cord in standing position before and during a valsalva maneuver. Additionally, scrotal Doppler and lower extremity venous Doppler ultrasonography were performed. Patients who were with spermatic varicose vein larger th . . .an 3.0 mm were included in the study group as a varicocele patient. At the lower extremity venous Doppler ultrasonography, a retrograde flow lasting longer than 0.5 seconds during normal breathing or at the valsalva maneuver was considered to be meaningful for saphenofemoral junction insufficiency. Thirty-six (51.35%) patients had insufficiency in saphenofemoral junction in the study group (6 [8.5%] bilateral, 30 [42.85%] unilateral) whereas 8 (26.6%) had insufficiency in the control group (2 [6.6%] bilateral, 6 [20%] unilateral insufficiency). The patients with primary varicocele had a statistically significant (P 5 .02) higher rate of venous insufficiency in their saphenofemoral junctions when compared with the control group. In the present study, the rate of saphenofemoral insufficiency has been found to be statistically higher in patients with primary varicocele compared with healthy men. Depending on the common presence of valvular insufficiency, we believe that the presence of varicocele should be investigated in the young population suffering from saphenofemoral junction insufficiency Daha fazlası Daha az

Erturhan, S. | Bayrak, O. | Sarica, K. | Seckiner, I. | Baturu, M. | Sen, H.

Article | 2013 | Urology81 ( 3 ) , pp.640 - 643

Objective: To evaluate the possible efficacy of an ?1 blocker (doxazosin) therapy on the management and disease course in pediatric patients with distal ureteral stones. Materials and Methods: A total of 45 patients (24 boys and 21 girls) with a single lower ureteral stone were included in the study program. Their age range was 3-15 years (mean 6.65 ± 3.78). The children were randomized into 2 main groups: group 1 (n = 21), who received only ibuprofen 20 mg/kg/d divided into 2 equal doses for pain control during follow-up; and group 2 (n = 24), who received, in addition to ibuprofen, 0.03 mg/kg/d doxazosin once daily, before bed. Re . . .sults: The stone expulsion rate was 28.5% (6 of 21) in group 1 and 70.8% (17 of 24) in group 2 (P = .001). The number of daily colic attacks and stone expulsion time clearly demonstrated the advantage of doxazosin, with a statistically significant diminished number of pain attacks (P = .04) and shorter stone expulsion period (P =.001). Stones <5 mm were expulsed at greater rates than stones 5-10 mm in group 2 (P =.046). Also children aged <6 years passed the stones with significantly greater rates than children aged ?7 years (P =.008). Conclusion: The use of ?-adrenergic blocker agents could have certain advantages in attempts to render children stone free within a shorter period, which would inevitably diminish the number of colic attacks and the need for analgesic usage. © 2013 Elsevier Inc. All Rights Reserved Daha fazlası Daha az

Yencilek, F. | Sarica, K. | Erturhan, S. | Yagci, F. | Erbagci, A.

Article | 2010 | Urologia Internationalis84 ( 3 ) , pp.260 - 264

Objectives: To evaluate the efficacy of semirigid ureteroscopy in the management of ureteral stones located in different parts of the ureter. Methods: 1,503 patients were treated with semirigid ureteroscopy. All ureteral stones were either removed only by a basket catheter or disintegrated by pneumatic lithotripsy. Success rates, auxiliary procedures, complication rates and operation time were comparatively evaluated according to stone location. Results: Overall, mean stone size and age were 12.1 ± 3.7 mm and 43.2 ± 9.72 years, respectively. While 1,416 patients (94.2%) were completely stone-free, the procedure was unsuccessful in 8 . . .7 cases (5.8%). The success rate was relatively low in the proximal ureter (71.7%) when compared with the mid (94.8%) and distal ureter (98.9%) (p = 0.021). Mean operation time was 25.4 ± 11.7 min. Longer duration of operation and higher complication rate were found in proximal ureteral calculi. Stone migration to the kidney and hematuria were the main reasons of failure in the proximal ureter and ureteral stenting was needed for 56.4% of patients with upper ureteral stone. Conclusions: Semirigid ureteroscopy can be the treatment of choice in lower and midureteral stones. However, it is an invasive and less successful treatment modality for proximal ureteral stones with relatively high complication rates. © 2010 S. Karger AG, Basel Daha fazlası Daha az

Tanriverdi, O. | Sarica, K.

Note | 2011 | Urology78 ( 3 ) , pp.521 - 522

[No abstract available]

Erturhan, S. | Bayrak, O. | Sarica, K.

Letter | 2013 | Urology81 ( 6 ) , pp.1381 - 1382

[No abstract available]

Sarica, K. | Yencilek, F. | Eryildirim, B. | Kuyumcuoglu, U.

Letter | 2009 | Urology74 ( 6 ) , pp.1378 - 1379

[No abstract available]