Kızılcık, Nurcan | Özler, Turhan | Menda, Ferdi | Uluçay, Çagatay | Köner, Ozge | Altıntaş, Faik

Article | 2017 | Acta Orthopaedica et Traumatologica Turcica51 ( 2 ) , pp.104 - 109

Objective: The aim of this study was to compared the effectiveness of intraarticular levobupivacain withlevobupivacain and magnesium sulfate.Methods: In this prospective randomized double blinded study, 96 patients (67 male, 29 female; agerange: 18e65 years) with ASA (American Society of Anesthesiologist) score I and II, who had undergonearthroscopic meniscectomy operation, were divided to 3 groups that had postoperative analgesia withintra-articular saline injection (control group), levobupivacain injection (L group) or levobupivacain andmagnesium sulfate injection (LM group). Patients were compared with postoperative VAS (Visual A . . .nalogScore) score during rest and activity, opioid analgesic need, non-opioid analgesic need and othermedication needs.Results: Postoperative VAS scores during rest and activation at early postoperative period were signiŞcantly lower at LM group when compared with L group and lower than control group at all time periods.Opioid analgesic need, non-opioid analgesic need and other medication needs for non-pain symptomswere lower at LM group when compared with L and control groups at all time periods.Conclusion: Intraarticular magnesium sulfate plus Levobupivacain injection is a safe and effectivemethod for post operative pain management after arthroscopic meniscectomy.Keywords: Intra-articular injection, Magnesium sulfate, Levobupivacain, Postoperative analgesia, Chondrocyte apoptosis, Pain management, Arthroscopic menisectomyLevel of Evidence: Level I, Therapeutic study© 2017 Turkish Association of Orthopaedics and Traumatology. Publishing services by Elsevier B.V. This isan open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/) Daha fazlası Daha az

Özler, Turhan | Uluçay, Çağatay | Önal, Ayberk | Altıntaş, Faik

Other | 2015 | Acta Orthopaedica et Traumatologica Turcica49 ( 3 ) , pp.255 - 259

Objective: Prevention of deep venous thrombosis (DVT) and associated pulmonary embolism following major orthopedic surgeries is challenging, and there is an increased interest in developing new treatment strategies. We compared 2 switch-therapy modalitiesenoxaparin to rivaroxaban and enoxaparin to dabigatranand enoxaparin monotherapy for preventing DVT after total knee arthroplasty (TKA) and total hip arthroplasty (THA). Methods: This was a prospective, non-blinded, randomized controlled study. We selected 180 eligible patients out of 247 patients undergoing TKA or THA. During the preoperative checkup, patients were randomized to re . . .ceive either enoxaparin (enoxaparin group) or switch-therapy regimens, comprising enoxaparin during hospitalization and rivaroxaban (rivaroxaban group) or dabigatran (dabigatran group) during the outpatient period. All patients were evaluated for DVT using Doppler ultrasonography (USG) 6 weeks postoperatively. The primary efficacy outcome was the prevention of symptomatic or Doppler ultrasonography (USG)-proven DVT, whereas the primary safety outcome was the incidence of bleeding during the DVT-prophylaxis period. Results: Doppler USG at 6 weeks after surgery revealed no signs of DVT in any patient. During the hospitalization period, only 2 major bleeding events were reported (1 [1.6%] in the enoxaparin group and 1 [1.6%] in the dabigatran group). No major bleeding events were reported during the outpatient follow-up period in any group. Differences among the 3 groups regarding bleeding events were not statistically significant (p>0.05). Conclusion: When using switch-therapy modalities, clinicians can take advantage of the safety of enoxaparin during the hospitalization period and ease of use of new oral anticoagulant drugs during the outpatient period Daha fazlası Daha az

Özler, Turhan | Güven, Melih | Önal, Ayberk | Uluçay, Çağatay | Beyzadeoğlu, Tahsin | Altıntaş, Faik

Article | 2014 | Acta Orthopaedica et Traumatologica Turcica48 ( 3 ) , pp.249 - 252

Amaç:Bu çalışmada tanısı atlanmış izole posterior malleol kırıklı hastaların yaralanma mekanizması ve klinik ve radyolojik sonuçlar açısından değerlendirilmesi amaçlandı. Çalışma planı: Atlanmış izole posterior malleol kırığı olan 7 hasta (5 erkek, 2 kadın, ortalama yaş 32 (23-40)) çalışmaya alındı. Ayak bileği burkulması nedeniyle acil servise başvuran ve standart ayak bilek grafileri ile kırık saptanmayan bu 7 hastada şikayetlerin devam etmesi nedeniyle 3. haftada çekilen ayak bileği MR görüntülemesi ile izole posterior malleol kırığı tanısı koyuldu. Hastalar 3 hafta boyunca yük kısıtlaması ve ayak bilekliği ile tedavi edildiler. . . .Kırık kaynamasının ve olası dejeneratif değişikliklerin değerlendirilmesinde ayak bileğinin ön-arka, yan ve 50 dış rotasyonda çekilen grafileri kullanıldı. Bütün hastalar 1 yıl takip edildi. Bulgular: Altıncı hafta sonunda 7 hastanın 6’sında kırık kaynaması görüldü. Bir hastanın ise 6. ayda hala kırığı kaynamamıştı. Hastaların ortalama AOFAS ayak bileği ardayak skorları tedavi öncesi ve tedavi sonrası 3. ayda sırası ile 20 (11-31) ve 86 (43-96) idi. Birinci yıl takiplerinde hiçbir hastada dejeneratif değişiklik veya instabilite saptanmadı. Çıkarımlar: Ayak bileği arkasında ağrı yakınması olan ve plantar fleksiyon ve/veya aksiyel kompresyon mekanizması ile ayak bileği burkulması tarif eden hastalarda izole posterior malleol kırığı akla getirilmelidir. Tanıda 50 dış rotasyonda çekilen yan grafi kırığın saptanmasına yardımcı olabilir. Objective:The aim of this study was to evaluate the injury mechanism and clinical and radiological results of the patients with isolated posterior malleolar fracture. Methods: Seven patients (5 male, 2 female; mean age: 32 years; range: 23-40) with a missed isolated posterior malleolar fracture were included in the study. All patients had initially been examined for an ankle sprain in the emergency room, where the initial plain radiographs did not show any abnormality. Due to the long lasting symptoms all patients underwent an MRI scan by the 3rd week which revealed a posterior malleolar fracture. Patients were treated with an ankle brace for 3 weeks. All patients were followed up for 1 year. Bone healing and degenerative changes were evaluated with plain Radiographs, including a 50° external rotation lateral. Clinical outcome was evaluated with American Orthopedic Foot and Ankle Society ankle hindfoot scale. Results: Fracture healing was seen in 6 of the 7 patients by the 6th week. There was no radiographic healing by 6th month in the remaining patient. Mean AOFAS ankle hindfoot scores at the beginning of the treatment and at 3rd month were 20 (11-31) and 86 (43-96), respectively. There was no instability or degenerative changes at one-year follow-up. Conclusion: Isolated posterior malleolar fracture should be kept in mind in patients who present with pain at the posterior part of the ankle following a forced plantar flexion and/or axial compression injury. A 50° external rotation lateral radiograph can be useful in detecting the fracture Daha fazlası Daha az

Servet, Erkan | Bekler, Halil | Kılınçoğlu, Volkan | Özler, Turhan | Özkut, Afşar

Other | 2016 | Acta Orthopaedica et Traumatologica Turcica50 ( 2 ) , pp.234 - 241

Objective: Epineural scar formation is one of the most significant negative factors affecting surgical repair after peripheral nerve injury. The scar tissue mechanically hinders axonal regeneration and causes adhesions between nerves and surrounding tissues. A hemostatic agent Ankaferd Blood Stopper (ABS; İmmun Gıda İlaç Kozmetik San. ve Tic. Ltd. Şti., Istanbul, Turkey) has not been previously used. Decreasing the postoperative bleeding and adhesions between nerve and surrounding tissues will prevent the formation of scar tissue, as well as corresponding compressive neuropathy and/or deceleration of axonal regeneration. The . . .purpose of this experimental study was to investigate the effects of bleeding on nerve healing and scar tissue after repair of peripheral nerve injuries.Methods: The right sciatic nerve of 30 Sprague-Dawley male rats (weighing 260-330 g) was cut 1.5 cm proximal to the trifurcation and repaired primarily with 8/0 sutures using epineural technique. The rats were then divided into 3 groups. Saline was applied in Group 1 (n10), ABS in Group 2 (n10), and heparin in Group 3 (n10) for 5 minutes to the repair site and surrounding tissues. In each group, electrophysiological measurements were performed with electromyography (EMG) at postoperative week 12. Magnetic resonance diffusion tensor imaging was used at week 12. Macroscopical and histopathological evaluations were conducted after sacrificing the rats at week 24 with total excision of the repaired sciatic nerves and surrounding tissues.Results: The ABS and saline groups showed better healing than the heparin group. The ABS and saline groups were better in the histopathologic evaluations, but there was no statistically significant difference between the 2 groups.Conclusion: Statistically significant differences were not found between the 3 groups. Significant results may be obtained with larger studie Daha fazlası Daha az

Özler, Turhan | Güven, Melih | Kocadal, Abdurrahman Onur | Uluçay, Çağatay | Beyzadeoğlu, Tahsin | Altıntaş, Faik

Article | 2012 | Acta Orthopaedica et Traumatologica Turcica46 ( 4 ) , pp.237 - 242

Amaç: Çalışmamızda erişkin klavikula orta diafiz kırıklarında açık redüksiyon ve kilitli anatomik plaklarla uygulanan internal tespit yönteminin sonuçlarını ve komplikasyonlarını değerlendirmeyi amaçladık. Çalışma planı: Ayrışmış-parçalı klavikula orta diafiz kırıklarına yönelik açık redüksiyon ve kilitli anatomik plakla tespit uygulanmış en az bir yıl takipli toplam 16 hasta (11 erkek, 5 kadın; ortalama yaş 39.6 yıl) geriye dönük değerlendirildi. Hastaların son takiplerinde erken ve geç dönem komplikasyonları ve Constant ve DASH skorlama sistemine göre fonksiyonel skorları değerlendirildi. Bulgular: Olguların ortalama takip süresi . . .24.6 (dağılım: 12-52) ay, ortalama kaynama süresi 13.3 (dağılım: 10-23) hafta idi. Erken dönemde hiçbir hastanın yara yerinde yüzeysel ve/veya derin enfeksiyon görülmedi ve nörovasküler komplikasyonla karşılaşılmadı. İki (%12.5) hastada implant irritasyonu tespit edildi. Geç dönemde iki (%12.5) hastada implant yetmezliğiyle karşılaşıldı. Bu hastalarda kaynama gecikmesi olduğu düşünülerek 4. ayda daha uzun plakla tespit ve otojen grefonaj uygulandı. Son takiplerde kaynamama ve hatalı kaynama sorunu olan hasta yoktu ve ortalama fonksiyonel skorları Constant skorlamasına göre 85.5, DASH skorlamasına göre 12.8 idi. Constant skorlaması komplikasyonlu hastalarda (p0.007), DASH skorlaması ise komplikasyonsuz hastalarda (p0.001) istatistiksel olarak anlamlı derecede düşük idi. Çıkarımlar: Ayrışmış orta diafiz klavikula kırıklarında kilitli anatomik plaklarla uygulanan tespitlerde komplikasyon oranı düşüktür. Cerrahi sonrası yaşanabilecek komplikasyonlar genellikle implant irritasyonu ve implant yetmezliği ile ilişkilidir. İmplant teknolojisindeki gelişmeler ve yeni implant tasarımlarıyla bu sorunların önüne geçilebilir. Objective: We aimed to evaluate the results and complications of open reduction and internal fixation by locked anatomic plates in adult midshaft clavicular fractures. Methods: Sixteen patients (11 males, 5 females; mean age: 39.6 years) who underwent open reduction and internal fixation with locked anatomic plate for displaced-comminuted midshaft clavicular fractures and were followed-up for at least one year were reviewed retrospectively. Complications in the early and late postoperative periods and functional scores according to the Constant and DASH scoring systems from the latest follow-up were evaluated. Results: Mean follow-up period was 24.6 (range: 12 to 52) months and mean union time was 13.3 (range: 10 to 23) weeks. None of the patients had superficial and/or deep infections in the early postoperative period or neurovascular complications. Two (12.5%) patients had implant irritation. In two (12.5%) patients, implant failure was detected in the late postoperative period. Delayed union was suspected in these patients and they were operated with longer plate and grafting in the 4th month. At the final follow-up, none of the patients had nonunion or malunion and the mean Constant and DASH scores were 85.5 and 12.8, respectively. Constant scores in patients with complications (p0.007) and DASH scores in patients with no complications (p0.001) were significantly lower. Conclusion: Fixation with locked anatomic plates in displaced midshaft clavicular fractures has lower complication rates. Possible postoperative complications are generally associated with implant irritation and failure. These problems can be avoided with the development in implant technology and new implant designs Daha fazlası Daha az