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Intestinal vaginoplasty: Seven years' experience of a tertiary center

A. Karateke | B. Haliloglu | O. Parlak | C. Cam | H. Coksuer

Article | 2010 | Fertility and Sterility94 ( 6 ) , pp.2312 - 2315

Objective: To investigate the long-term effects of intestinal vaginoplasty in cases with Mayer-Rokitansky-Kuster-Hauser (MRKH) syndrome. Design: Prospective study. Setting: Division of Pelvic Reconstructive Surgery, Department of Gynecology and Obstetrics, at a women's and children disease education and research hospital. Patient(s): Between 2003 and 2009, 29 patients with MRKH syndrome underwent intestinal vaginoplasty. Intervention(s): Two of the patients were treated with ileal and 27 with sigmoid vaginoplasty. Main Outcome Measure(s): The age, marital status, associated anomalies, method used for bowel transposition (isoperistal . . .tic/antiperistaltic), type of abdominal incision, and intra- and postoperative complications were evaluated. Result(s): One of the patients for whom ileal vaginoplasty was performed had 40 cm ileal necrosis requiring bilateral ileostomy for 2 months. Introital stenosis was detected in 15 cases (79%) who were unmarried, while none of the married cases had introital stenosis. However, all patients responded to finger-dilatation. All married patients were sexually satisfied after operation. An intraluminal abscess developed in the proximal segment of the neovagina owing to stricture occurring above abdominoperineal tunnel 2 years after operation. In another patient who had a rudimentary uterine horn, hematometra developed 3 years after operation and treated with resection. Conclusion(s): In our experience, sigmoid vaginoplasty seems to be a favorable procedure which provides excellent long-term results for the patients with vaginal agenesis. Copyright © 2010 American Society for Reproductive Medicine, Published by Elsevier Inc Daha fazlası Daha az

Coronary artery bypass surgery provokes alzheimer's disease-like changes in the cerebrospinal fluid

A. Palotás | H.J. Reis | G. Bogáts | B. Babik | M. Racsmány | L. Engvau | J. Kálmán

Article | 2010 | Journal of Alzheimer's Disease21 ( 4 ) , pp.1153 - 1164

Several biomarkers are used in confirming the diagnosis of cognitive disorders. This study evaluates whether the level of these markers after heart surgery correlates with the development of cognitive dysfunction, which is a frequent complication of cardiac interventions. Concentrations of amyloid-ß peptide, tau, and S100ß in the cerebro-spinal fluid were assessed, as well as cognitive functions were evaluated before and after coronary artery bypass grafting, utilizing immuno-assays and psychometric tests, respectively. A drastic rise in the level of S100ß was observed one week after the surgery, a mark of a severe generalized cereb . . .ral injury. The level of amyloid-ß peptide significantly decreased, whereas the concentration of tau markedly increased six months postoperatively. Gradual cognitive decline was also present. These findings clearly demonstrate post-surgical cognitive impairment associated with changes in biomarkers similar to that seen in Alzheimer's disease, suggesting a unifying pathognomic factor between the two disorders. A holistic approach to coronary heart disease and Alzheimer's-type dementia is proposed. © 2010 IOS Press and the authors. All rights reserved Daha fazlası Daha az

An econometric analysis of the aggregate outbound tourism demand of Turkey

F. Halicioglu

Article | 2010 | Tourism Economics16 ( 1 ) , pp.83 - 97

This study empirically examines aggregate tourism outflows in the case of Turkey using the time-series data for 1970-2005. As far as this article is concerned, there is no previous empirical work dealing with tourist outflows from Turkey. The previous tourism studies of Turkey have focused, by and large, on inbound tourism demand analyses. However, as a developing country and an important tourism destination, Turkey has also been a significant source for generating a substantial number of tourists in recent years. Therefore, the tourist outflows also merit empirical analysis. Total tourist outflows from Turkey are related to real in . . .come and relative prices. The bounds testing to cointegration procedure proposed by Pesaran et al (2001) is employed to compute the short- and long-run elasticities of income and relative prices. An augmented form of Granger causality analysis is conducted among the variables of outbound tourist flows, income and relative prices to determine the direction of causality. In the long run, causality runs interactively through the error correction term from income and relative prices to outbound tourist flows. However, in the short run, causality runs only from income to outbound tourism flows. The aggregate tourism outflows equation is also checked for the parameter stability via the tests of cumulative sum (CUSUM) and cumulative sum of the squares (CUSUMSQ). The results suggest that income is the most significant variable in explaining total tourist outflows from Turkey and there is a stable outbound tourism demand function. The results also lead to important policy recommendations Daha fazlası Daha az

Design and implementation of a control architecture for robot-assisted orthopaedic surgery

Barkana, D.E.

Article | 2010 | International Journal of Medical Robotics and Computer Assisted Surgery6 ( 1 ) , pp.42 - 56

Background: Recent research in orthopaedic surgery indicates that computer-assisted robotic systems improve the precision and accuracy of the surgery, which in turn leads to better long-term outcomes. Increasing demand for minimally invasive bone-cutting operations has been encouraging surgical robot developments in orthopaedics. An orthopaedic robotic system and an intelligent control architecture that will be used in bone-cutting operations were developed. Methods: An orthopaedic surgical robotic system called OrthoRoby was developed. A computed-torque low-level control method was used for OrthoRoby to track a desired bone-cutting . . . trajectory. Kinematic and dynamic analysis of OrthoRoby was derived for control purposes. An intelligent control architecture was designed that systematically combines a high-level controller with a computed-torque low-level controller to complete bone-cutting operations in a desired and safe manner. Results: A series of experimental tests were conducted on a bone model to evaluate the performance of the intelligent control architecture. Experimental results demonstrated that the intelligent control architecture could monitor the progress and the safety of the cutting operation, such that necessary dynamic modifications could be made to complete the bone-cutting operation in a safe manner. Conclusions: The experiments performed on the OrthoRoby robotic system and its intelligent control architecture yielded promising results. Although minor problems still exist at the prototype stage, minor modifications of the OrthoRoby and intelligent control architecture would be a significant step towards the use of the OrthoRoby and its intelligent control architecture in a surgical operation. Copyright © 2009 John Wiley & Sons, Ltd Daha fazlası Daha az

Modeling a supply chain as a queuing system

Toktas-Palut, P. | Ülengin, F.

Conference Object | 2010 | IFAC Proceedings Volumes (IFAC-PapersOnline) , pp.242 - 247

This study investigates a two-stage supply chain consisting of multiple suppliers at the first stage and a manufacturer at the second stage. The suppliers and the manufacturer have limited production capacities. The system operates in a manufacture-to-order environment, i.e. the suppliers and the manufacturer employ make-to-stock and make-to-order strategies, respectively. The inventory of each component at each supplier is controlled via base stock policy. The aim of this study is to model the supply chain as a queuing system. Under the necessary assumptions, each supplier is modeled as an M / M /1make-to-stock queue. Moreover, the . . . average outstanding backorders and the average inventory level of each supplier are derived using the queuing model. On the other hand, the manufacturer is modeled as a GI / M /1 queue after deriving an approximate distribution for the interarrival times of the manufacturer. Furthermore, the average number of jobs in the manufacturer's system and the average outstanding backorders at the manufacturer are obtained using the queuing model. © 2010 IFAC Daha fazlası Daha az

Assessment of effects of antiplatelet drugs on bleeding risk after teeth extractions

Duygu, G. | Ozcakir-Tomruk, C. | Guler, N. | Sencift, K.

Article | 2010 | Biotechnology and Biotechnological Equipment24 ( 3 ) , pp.2040 - 2043

The aim of this study was to determine the bleeding risk after teeth extractions among patients on daily doses of Aspirin® (ASA) in the range of 75 mg to 300 mg. Forty-four patients, under antiplatelet treatment, referred to our clinic for teeth extractions. ASA interrupted 7 days before dental extractions served as control group (19 patients), while study group had their ASA regimen regularly administered (25 patients). Investigation of bleeding time (BT) was performed on the day of extractions. Managing postoperative bleeding differs from local pressure by gauze to locally applied tranexamic acid. The mean BT was within normal lim . . .its in both groups. When compared in terms of BT, a statistical significance was found (p=0.001) between the groups. When compared in terms of bleeding control the difference between the groups was significant (p=0.008). We may conclude that most minor oral surgery procedures can be carried out safely without interruption of long-term ASA regimen Daha fazlası Daha az

Ex vivo evaluation of antibacterial effects of Nd:YAG and diode lasers in root canals

Gerek, M. | Asci, S. | Yaylali, D.I.

Article | 2010 | Biotechnology and Biotechnological Equipment24 ( 3 ) , pp.2031 - 2034

The presence of necrotic tissue and bacteria may cause the persistence of infection in root canals. The aim of this study is to compare the antibacterial efficacy of standard irrigating procedures with 2.5% NaOCl and 17% EDTA using the laser techniques of Nd:YAG and Diode lasers on 176 extracted single-rooted teeth. Strains of Enterococcus faecalis and Candida albicans were used. After the tests were performed, the number of colony-forming units per milliliter (CFU/ml) was counted and the results were statistically analyzed. According to the data evaluated, although EDTA, Nd:YAG, and Diode lasers were effective as a bactericidal age . . .nt in contaminated root canals, NaOCl had a significantly higher antibacterial effect. The Nd:YAG and Diode lasers showed more antimicrobial effect than EDTA in the E. faecalis group while the Nd:YAG and Diode lasers and EDTA showed the same level of antimicrobialaction in the C. albicans group Daha fazlası Daha az

Clinical and phenomenological features in pediatric bipolar disorder

Coskun, M | Zoroglu, SS | Ozturk, M


Retrospective studies in adults with bipolar disorder have reported that as many as 60% experienced the onset of their bipolar disorder before 20 years of age, and 10-20% reported the onset before 10 years of age. These findings make childhood and adolescence onset bipolar disorder more relevant as early recognition and intervention in psychiatric disorders have been increasingly important. Today, despite there is no doubt on the existance of pediatric bipolar disorder, there remains significant controversy about clinical and phenomenological features of disorder in children and adolescents. This review article aims to present and d . . .iscuss clinical and phenomenological features of pediatric bipolar disorder in the light of current literature. We performed a search on Pubmed using keywords 'juvenile/pediatric bipolar disorder', 'bipolar disorder children/adolescents' and reviewed fulltext or abstracts of relevant articles. We also benefited from print books particularly the fourth edition of Lewis's Textbook of Child and Adolescent Psychiatry. (Anatolian Journal of Psychiatry 2010; 11:60-67 Daha fazlası Daha az

Better glycemic control with insulin premix 50/50 TID compared to insulin premix 70/30 BID

Aydin, H. | Demir, H. | Şienkal, I.V. | Yalniz, F.F. | Ayrilmaz, A.

Article | 2010 | Turkish Journal of Endocrinology and Metabolism14 ( 3 ) , pp.60 - 65

Objective: Since only a small proportion of diabetics achieve optimal glycemic targets, intensification of treatment with insulin is needed in most of the cases. Application of insulin lispro premix 50/50 TID provides better glycemic control compared to human insulin premix 70/30 and comparable results reported with basal-bolus insulin regimen. The aim of this study was to determine the effect of insulin lispro premix 50/50 TID (Group 1, n=60) in comparison with insulin aspart premix 70/30 (Group 2, n=62). Materials and Methods: Type 2 diabetic patients, who were started on insulin treatment for the first time, were screened retrosp . . .ectively. Change in A1C levels, 4-point self-monitored blood glucose measurements and rate of hypoglycemia within a 3-month period were recorded. Results: Basal A1C levels were higher (p=0.002) and the rate of improvement was greater in patients of Group 1 than in Group 2 patients (p=0.0006). There was no difference between the patients in achieving target A1C level and in the rate of hypoglycemia. A greater decrease in postprandial blood glucose level was achieved in patients of Group 1 ( Daha fazlası Daha az

Assessment of anterior chamber depth using visante optical coherence tomography, slitlamp optical coherence tomography, IOL Master, Pentacam and Orbscan IIz

Dinc, U.A. | Gorgun, E. | Oncel, B. | Yenerel, M.N. | Alimgil, L.

Article | 2010 | Ophthalmologica224 ( 6 ) , pp.341 - 346

Aims: To assess and compare the anterior chamber depth (ACD) by different anterior segment imaging techniques. Methods: Eighty healthy eyes of 40 patients were recruited, and 3 consecutive measurements of ACD were determined prospectively utilizing Visante optical coherence tomography (OCT), slitlamp (SL) OCT, IOL Master, Pentacam and Orbscan IIz. The statistical significance of interdevice differences between measurements was evaluated by one-way ANOVA and Bland-Altman analysis. The repeatability of 3 consecutive measurements was analyzed by repeated-measures ANOVA. Results: The mean ACD was 2.98 ± 0.29, 2.85 ± 0.29, 3.33 ± 0.42, 2 . . ..93 ± 0.30 and 2.80 ± 0.29 mm with Visante OCT, SL-OCT, IOL Master, Pentacam and Orbscan IIz, respectively. All devices displayed a high intrasession repeatability (repeated-measures ANOVA, p > 0.05). ACD measurements obtained by the IOL Master were significantly greater compared to other devices. ACD values detected by Visante OCT and SL-OCT, Pentacam and Orbscan IIz were not clinically interchangeable, even though no statistically significant difference was detected. Conclusion: Although noncontact ACD measurements using all modalities were easy to handle and demonstrated good repeatability, the tested devices were not regarded as compatible. Hence, the clinician should take the different modalities into consideration during ACD assessment using various devices. Copyright © 2010 S. Karger AG, Basel Daha fazlası Daha az

Dirichlet problems for the generalized n-poisson equation

Aksoy, Ü. | Çelebi, A.O.

Conference Object | 2010 | Operator Theory: Advances and Applications205 , pp.129 - 141

Polyharmonic hybrid Green functions, obtained by convoluting polyharmonic Green and Almansi Green functions, are taken as kernels to define a hierarchy of integral operators. They are used to investigate the solvability of some types of Dirichlet problems for linear complex partial differential equations with leading term as the polyharmonic operator. © 2009 Birkhäuser Verlag Basel/Switzerland.

Solution of initial value problems of Cauchy-Kovalevsky type in the space of generalized monogenic functions

Yüksel, U. | Çelebi, A.O.

Article | 2010 | Advances in Applied Clifford Algebras20 ( 2 ) , pp.427 - 444

This paper deals with the initial value problem of the type, where t ? R0+ is the time, x ? Rn+1 is a generalized monogenic function and the operator L, acting on a Clifford-algebra-valued function, with real-valued components uB(t, x), is defined by, We formulate sufficient conditions on the coefficients of the operator L under which L transforms generalized monogenic functions again into generalized monogenic functions. For such an operator the initial value problem (0.1) is solvable for an arbitrary generalized monogenic initial function u0 and the solution is also generalized monogenic for each t. © 2010 Birkhäuser / Springer Ba . . .sel AG, Switzerland Daha fazlası Daha az

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