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Bulunan: 525 Adet 0.002 sn
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Role of mTOR (Mammalian Target of Rapamycin) Signal Mechanism in the Treatment of Polycystic Ovary Syndrome (PCOS).

Ucar, AY | Aydin, MS | Agus, S | Gunalan, E | Yildirim, E | Yılmaz, B

Conference Object | 2017 | REPRODUCTIVE SCIENCES24

Bir Hastanede Çalışan Hemşirelerin İlaç Hatası Bilgi Düzeyi ve İlaç Hatalarının Raporlanması ile İlgili Görüşlerinin Değerlendirilmesi

Aydın, Seçil Semiz | Akın, Semiha | Işıl, Özlem

Article | 2017 | Hemşirelikte Eğitim ve Araştırma14 ( 1 ) , pp.14 - 24

Amaç: Bu çalışma hemşirelerin ilaç hatası bilgi düzeyi ve ilaç hatalarının raporlanmasına ilişkin görüşlerinin değerlendirilmesi amacıyla planlandı.Yöntem: Tanımlayıcı-kesitsel nitelikte bir araştırmadır. Araştırma örneklemini 114 hemşire oluşturdu. Veriler, İlaç Hatalarının Raporlanmasına Yönelik Düşünceler ve İlaç Hatası Bilgi Durumunu Belirleme Formları kullanılarak elde edildi.Bulgular: Yaş ortalaması 29.377.10 olan hemşirelerin %51.8'i lisans mezunudur. İlaç Hatası Bilgi Durumu Belirleme Formu puan ortalaması 82.5217.19 bulundu. Araştırma grubunun çoğu (%94.7) ilaç güvenliği eğitimi aldığını, %78.1'i ilaç hatalarının raporlanma . . .sını başarı ölçütü olduğunu bildirdi. Hemşireler ilaç hatalarını raporlamaları durumunda %8.8'i bu hatanın kişisel yetersizlik olarak algılanacağını, %4.4'ü işinin tehlikeye gireceğini, %4.4'ü raporlamanın işe yaramayacağını düşünmektedir. Hemşirelerin üçte biri (%28.9) ilaç hatası ile ilgili sorunları kendi aralarında çözülebileceğini, %9.6'sı nasıl raporlama yapılacağını bilmediklerini, %0.9'u ise ilaç hatalarının raporlanmasına gerek olmadığını bildirdi. Sonuç: Verilen eğitimlerde ilaç hatalarının raporlamasını çalışanın cezalandırılması olarak algılanmaması gerektiği ve raporlama sürecinin hasta güvenliğinin sağlamaya yönelik önemli bir uygulama olduğunun vurgulanması önem taşımaktadır. Hemşirelerin ilaç hatası raporlama konusundaki bilgilerini daha etkin şekilde uygulamaya yansıtabilmeleri amacıyla kurumsal stratejilerin geliştirilmesi ve eğitimlerin planlanması önerilmektedir Aims: The aim of this study is to assess nurses’ levels of knowledge regarding medication errors and their views on reporting medication errors.Methods: The research adopted a descriptive, cross-sectional design and the study sample comprised 114 nurses. Data were gathered using two assessment forms: “Views on Reporting Medication Errors” and “Assessment of Knowledge of Medication Errors”.Results: The mean age of nurses was 29.377.10 years, 51.8% of the sample completed an undergraduate nursing program. The mean score of the “Assessment of Knowledge on Medication Errors” was 82.5217.19. Nearly all nurses (94.7%) completed training in medication safety, 78.1% of nurses perceived the act of medication error reporting as a successful criterion. In the case of reporting medication errors, 8.8% of nurses perceived that reporting medication errors can be considered a personal incompetency, 4.4% reported that it would put their job in jeopardy, and 4.4% stated it would be of no use to report errors. One out of every three nurses (28.9%) claimed any problem could be settled among themselves, 9.6% of them stated that they do not know how to report errors, and 0.9% of the nurses stated that there was no need for reporting any errors.Conclusion: In training sessions which encourage the staff to report medication errors for patient safety, it is important not to consider a medication error reporting system as a punishment for employees but as a crucial part of the system. It is suggested that corporate strategies be developed and training programs be planned in order to improve nurses’ skills for better reporting of medication error Daha fazlası Daha az

The effect of low-level laser therapy as an adjunct to non-surgical periodontal treatment on gingival crevicular fluid levels of transforming growth factor-beta 1, tissue plasminogen activator and plasminogen activator inhibitor 1 in smoking and non-smoking chronic periodontitis patients: A split-mouth, randomized control study

Pamuk, F. | Lütfioğlu, M. | Aydoğdu, A. | Koyuncuoglu, C.Z. | Cifcibasi, E. | Badur, O.S.

Article | 2017 | Journal of Periodontal Research52 ( 5 ) , pp.872 - 882

Background and Objective: This study aimed to investigate the effects of low-level laser therapy (LLLT) as an adjunct to scaling and root planing (SRP) on smoking and non-smoking patients with chronic periodontitis. Material and Methods: The study was conducted using a split-mouth design with 30 patients with chronic periodontitis (15 smokers, 15 non-smokers) and 30 healthy individuals matched for age, sex and smoking status as controls. Groups were constituted as follows: Cp+SRP+Sham: non-smokers with chronic periodontitis treated with SRP; Cp+SRP+LLLT: non-smokers with chronic periodontitis treated with SRP+LLLT; SCp+SRP+Sham: smo . . .kers with chronic periodontitis treated with SRP; SCp+SRP+LLLT: smokers with chronic periodontitis treated with SRP+LLLT; C: control group comprised of periodontally healthy non-smokers; SC: control group comprised of periodontally healthy smokers. LLLT was first applied on the same day as SRP and again on days 2 and 7 after SRP treatment. Clinical parameters were recorded before non-surgical periodontal treatment (baseline) and on day 30. Gingival crevicular fluid samples were collected before periodontal treatment (baseline) and during follow-up visits on days 7, 14 and 30. Gingival crevicular fluid transforming growth factor (TGF)-ß1, tissue plasminogen activator (tPA) and plasminogen activator inhibitor 1 (PAI-1) levels were measured using enzyme-linked immunosorbent assay. Results: All clinical parameters showed significant reductions between baseline and day 30 following SRP treatment in both the LLLT and sham groups (P.05). Gingival crevicular fluid PAI-1 levels decreased significantly in the SCp+SRP+sham and SCp+SRP+LLLT groups ( Daha fazlası Daha az

Electrochemically designed interfaces: Electrical properties and morphology of micro-nanostructured Titania implant surfaces

Utku, F.S.

Article | 2017 | Surface and Coatings Technology324 , pp.546 - 551

Designing Titanium implant interfaces is essential not only for the prevention of corrosion, but also for the promotion of osteointegration. Surface morphology and surface charge are crucial determinants in the construction of biocompatible osteoconductive orthopedic and dental implants. Thus, generation of surfaces with optimal topographic and electrical properties for cellular growth has been aimed. In this study, surface chemistry and morphology of cp Titanium plates were modified by anodization at 30 V for 60 min, in dual acidic solution (48 wt% H2SO4-18 wt% HCl) at 40 °C and in alkaline solution (5 M KOH) at 40°, 60° and 80 °C. . . . Titanium surfaces were characterized for morphology, crystallography, wettability, bulk resistivity, corrosion resistance, surface conductivity and capacitance. Morphological characterization using FE-SEM revealed micro-to-nanoscale porosity, with nanosized pores formed within the micropores, generating a hierarchically arranged micro-nano network on Titanium surfaces anodized under all thermal conditions. Hydrophilicity decreased with increasing alkaline anodization temperature (control, 100 ± 0.7° 40 °C, 23.3 ± 3.0° 60 °C, 43.5 ± 2.1° 80 °C, 55.3 ± 2.3°). The XRD analysis displayed only Ti peaks at 34.5°, 38°, 40°, 53° and 63° 2?. Increasing alkaline anodization temperature modified the electrical properties of Titanium plates. Mott-Schottky analysis displayed an increase in capacitance as indicated by steeper slopes and linearity extending over a greater potential range with increasing temperature. Corrosion current density (Icorr) was experimentally determined as 1.05 × 10- 7A/cm2, 5.95 × 10- 8A/cm2, 3.79 × 10- 9A/cm2, 3.92 × 10- 9A/cm2 while charge carrier density was calculated as 3.44 × 1020/cm3, 3.50 × 1019/cm3, 2.05 × 1019/cm3, 1.01 × 1019/cm3 respectively for the control, 40 °C, 60 °C and 80 °C samples. All things considered, samples modified in 5 M KOH solution at 60 °C displayed optimal micro-to-nanoporosity, lowest corrosion current density and anodic voltage. The electrical properties of modified Titanium surfaces have indicated that it may be more suitable to use Potassium hydroxide in the anodization of biomedical implants which require a biocompatible, osteoconductive topography, high capacitance and high corrosion resistance. © 201 Daha fazlası Daha az

Use of post-tensioned concrete slabs for sustainable design of buildings

Süleymanoglu, H. | Uzel, A. | Arslan, G.

Conference Object | 2017 | High Tech Concrete: Where Technology and Engineering Meet - Proceedings of the 2017 fib Symposium , pp.2390 - 2395

Post-tensioned concrete design can lead to considerable savings in materials, construction time and future maintenance costs, compared to the conventional reinforced concrete design. Pre-stressing improves the behaviour of concrete in tension. Thus, for the same imposed load, a more slender structure can be designed. Reduced slab depth results in reduced building height and savings in related building components. These savings translate into less material usage which means reduced embodied energy for a structure thus, creating a sustainable solution. In this study, buildings with post-tensioned and conventional reinforced concrete s . . .lab systems are compared. Two buildings with the same floor plans are designed using reinforced concrete and post-tensioned slab systems. The span length is chosen as 6.5 m, which is a practical limit for a relatively economical reinforced concrete solution. The buildings are designed as 10, 20 and 40 stories to demonstrate the change in material savings as the number of floors increases. Since post-tensioned slabs can be designed thinner for the same loads and spans, total weight of the structure reduces and this results in smaller columns, lower seismic loads and foundation loads. The results showed that the difference in steel material savings between conventional and post-tensioned solutions increases as the number of floors increases. It is concluded that incorporating post-tensioning into common design practice not only reduces construction costs but also reduces embodied energy by using less material and produces a sustainable structural design. ©Springer International Publishing AG 2018 Daha fazlası Daha az

Basut, L.L.

Review | 2017 | Filozofski Vestnik38 ( 1 ) , pp.7 - 21

Evaluation of Surface Roughness Characteristics Using Atomic Force Microscopy and Inspection of Microhardness Following Resin Infiltration with Icon®

E.B. Gurdogan | D. Ozdemir-Ozenen | N. Sandalli

Article | 2017 | Journal of Esthetic and Restorative Dentistry29 ( 3 ) , pp.201 - 208

Objective: The aim of this study was to evaluate the surface roughness via atomic force microscopy (AFM) as well as to evaluate the microhardness values of Icon® in comparison with sound and demineralized enamel in a large subject group. Materials and Methods: Enamel samples were prepared from sound bovine incisors and randomly allocated into either AFM (n = 60) or microhardness (n = 60) groups. The AFM group was divided into control (n = 30) and Icon® (n = 30) subgroups. The microhardness group was also divided into three subgroups: control (n = 20), demineralization (n = 20) and Icon® (n = 20) groups. The demineralization and Icon . . .® subgroups were subjected to a demineralizing solution (pH: 4, 2 hours). Following the formation of shallow white spot lesions and application of the infiltrant, each sample was examined according to its parameter. Results: AFM images suggested that Icon® had a significantly rougher surface than the control group. When the AFM results were evaluated numerically, it was evident that the Icon® group possessed statistically higher Sa, Sq, mean height, and maximum deviation values compared to the control group. The mean Vickers hardness values of all groups were determined to be significantly different from one another. Hardness values in the demineralization group were determined to be significantly lower than the control and Icon® groups. No statistically significant difference was observed between mean Vickers hardness values for the contol and Icon® groups. Conclusions: The present in vitro study shows that more studies are required to improve the surface quality of this infiltrant material. Clinical Significance: The present in vitro study shows that the resin infiltration technique results in increased microhardness of demineralized enamel. However, it was observed that the infiltrant material creates a significantly rougher surface compared to healthy, untreated enamel. (J Esthet Restor Dent 29:201–208, 2017). © 2016 Wiley Periodicals, Inc Daha fazlası Daha az

6102 SAYILI TTK’NIN KIYMETLİ EVRAK KİTABINA İLİŞKİN BAZI DEĞERLENDİRMELER

Bahtiyar, Mehmet

Article | 2017 | İstanbul Kültür Üniversitesi Hukuk Fakültesi Dergisi16 ( 2-Cilt 3 ) , pp.67 - 82

6102 Sayılı Türk Ticaret Kanunu’nun kıymetli evraka ilişkin hükümlerinde, eskisine oranla, çok az değişiklik yapılmıştır. Bu husus gerekçede de belirtilmiştir.Ne var ki; yapılan bazı değişikliklerin yerindeliği tartışmaya açıktır. Değişmesi veyahükme bağlanması gerektiği halde ele alınmayan hususlar da mevcuttur.Çalışmamızda, yapılan bazı değişiklik ve yenilikler ele alınarak, hükümlerin yerindeliği hakkında değerlendirme ve önerilerde bulunulmuştur. 6102 Nr. Turkish Commercial Code’s provisions regardingnegotiable instruments were slightly amended compared with previous provisons of6762 Nr. Turkish Commercial Code. This has also be . . .en stated in preamble. Howeversome provisions are disputable and there are also some matters that went unregulated orthat were not amended although there was a necessity.We dealt with and evaluated some of those amendments and new provisions of6102 Nr. Turkish Commercial Code’s provisions regarding negotiable instruments inour study Daha fazlası Daha az

Change of PD-L1 expression status of high grade glial tumors at recurrence and its effect on survival

Oyan, B | Eren, S | Sonmez, O | Ozkan, F | Yaltirak, K | Ture, U

Conference Object | 2017 | ANNALS OF ONCOLOGY28 , pp.67 - 82

Percentage and severity of periodontal diseases in Turkish adults aged 35+ years, 2009-10

Ilhan, D. | Oktay, I. | Nur, B. | Fisekcioglu, E. | Lim, S. | Lepkowski, J.M. | Ismail, A.I.

Article | 2017 | Journal of Public Health Dentistry77 ( 4 ) , pp.325 - 333

Objective: This article presents data on the burden of periodontal diseases in Turkish adults aged 35 years or older. Methods: Within each region of Turkey, a rural and an urban area or city were selected in 2009-10 using a probability proportional to size method. In the selected towns, local officials who were familiar with their communities assisted in recruiting subjects. Loss of Attachment (LOA) was measured at six sites around each tooth present in the mouth, excluding third molars. Additionally, the Community Periodontal Index was used to assess the severity of periodontal diseases around 12 index teeth. Self-reported data on . . .key risk factors were also collected. Weights were computed using a raking ratio adjustment procedure and used in all analyses. Results: Almost all examined adults had some loss of periodontal attachment. The proportion of those with more than 3 mm LOA ranged from 43 percent in 35-44 year olds to 91 percent in those aged 65+ years. Among females, older age, low education status, smoking 11-40+ cigarettes a day, being employed, and presence of high number of missing tooth surfaces were associated with LOA > 3 mm. Among males LOA >3 mm was associated with older age, use of alcohol, and unemployment. The CPI data did not yield the same associations with periodontal diseases and risk factors. Conclusions: Periodontal diseases in Turkish adults are highly prevalent. A tailored common risk factor health promotion program is recommended to reduce the burden of periodontal infection in Turkey. © 2017 American Association of Public Health Dentistr Daha fazlası Daha az

Analytical methods in tracing honey authenticity

Trifkovic, J. | Andric, F. | Ristivojevic, P. | Guzelmeric, E. | Yeşilada, Erdem

Article | 2017 | Journal of AOAC International100 ( 4 ) , pp.827 - 839

Honey is a precious natural product that is marketed with a wide range of nutritional and medicinal properties. However, it is also a product subjected to frequent adulteration through mislabeling and mixing with cheaper and lower-quality honeys and various sugar syrups. In that sense, honey authentication regarding its genuine botanical and geographical origins, as well as the detection of any adulteration, is essential in order to protect consumer health and to avoid competition that could create a destabilized market. Various analytical techniques have been developed to detect adulterations in honey, including measuring the ratio . . .s of stable isotopes (mostly 13C/12C) and the use of different spectroscopic, chromatographic, and electrochemical methods. This review aims to provide a cross-section of contemporary analytical methods used for the determination of honey authenticity in order to help the scientific community engaged in the field of honey chemistry make appropriate choices and select the best applications that should lead to improvements in the detection and elimination of fraudulent practices in honey manufacturing Daha fazlası Daha az

6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.

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