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Effect of air bubbles localization and migration after embryo transfer on assisted reproductive technology outcome

Fıçıcıoğlu, C. | Özcan, P. | Koçer, M.G. | Yeşiladalı, M. | Alagöz, O. | Özkara, G. | Altunok, Ç.

Article | 2018 | Fertility and Sterility109 ( 2 ) , pp.310 - 3140

Objective: To evaluate the effect of embryo flash position and movement of the air bubbles at 1 and 60 minutes after ET on clinical pregnancy rates (PRs). Design: Prospective clinical trial. Setting: University fertility clinic. Patient(s): A total of 230 fresh ultrasound-guided ETs performed by a single physician (C.F.) at the IVF center of Yeditepe University Hospital between September 2016 and February 2017 were included. Intervention(s): Transabdominal ultrasonographic guidance at ET. Main Outcome Measure(s): Clinical PRs. Result(s): There was no significant difference in terms of clinical PRs between women with embryo flash loc . . .ated >15 mm and Daha fazlası Daha az

Critical assessment of entrepreneurial and innovative universities index of Turkey: Future directions

Gür, U. | Oylumlu, İ.S. | Kunday, Ö.

Article | 2017 | Technological Forecasting and Social Change123 , pp.161 - 168

The aim of the paper is to present a new performance measurement concept and a relevant methodology for entrepreneurial universities which serves the ideal of transforming into an innovative one and contributing to the economic development and societal benefits. The current Entrepreneurial and Innovative Universities index which is in place in Turkey is evaluated according to the available perspectives in excellence of Higher Education Institutions and domains for advancement are being discussed. Furthermore, standard evaluation of the universities with ranking methodology is argued proposing a conceptual framework based on non-line . . .ar dynamics of systems thinking. Consequently, further directions in research, policy and university management are delivered putting forward the view that the entrepreneurial university ecosystem requires innovative approach in all aspects. © 2016 Elsevier Inc Daha fazlası Daha az

Holocord Pilocytic Astrocytoma in an Adult: A Rare Case Report and Review of the Literature

Baran, O. | Kasimcan, O. | Sav, A. | Oruckaptan, H.

Article | 2019 | World Neurosurgery126 , pp.369 - 375

Background: Intramedullary glial neoplasms affecting the entire spinal cord from the cervicomedullary junction to conus medullaris are termed holocord tumors. Pilocytic astrocytomas are relatively uncommon tumors forming holocord involvement. Hitherto 24 holocord astrocytoma cases were reported in the literature. Here, a case of an adult holocord pilocytic astrocytoma was presented. Case Description: A 29-year-old female patient presented with a subtotal resection. Histopathologic examination revealed pilocytic astrocytoma, World Health Organization grade 1, presenting holocord involvement. Magnetic resonance imaging showed a mass c . . .ontaining necrotic and cystic foci leading to an expansion along the entire spinal cord extending from C4 to conus medullaris. Conclusions: Reported holocord pilocytic astrocytomas in the relevant literature cases were reviewed. When evaluating magnetic resonance imaging scans of adult patients with various neurologic symptoms, i.e., weakness and fecal and urinary incontinence, pilocytic astrocytoma should be considered among differential diagnoses of intramedullary mass lesions. © 2019 Elsevier Inc Daha fazlası Daha az

CO2 Capturing Materials

Davran-Candan, T.

Book Part | 2018 | Comprehensive Energy Systems02.05.2020 , pp.881 - 912

Carbon capture and sequestration (CCS) emerges as a viable option for reducing atmospheric CO2 concentrations required for the mitigation of global warming and a sustainable energy future. The first step of CCS, which is the separation of CO2 from flue gas, is still very expensive limiting its use for industrial scale operations; so there is an extensive research going on, for the development of feasible capture materials. This chapter aims to provide a basic understanding about the current status and future directions of this search, providing an extensive literature review about the subject in addition to an illustrative example t . . .hat comparatively analyses materials for a better understanding of the factors affecting the adsorption capacity. © 2018 Elsevier Inc. All rights reserved Daha fazlası Daha az

A conceptual view of exergy destruction in mergers and acquisitions

Olcay, G.A. | Öner, M.A. | Olcay, A.B.

Article | 2019 | Technological Forecasting and Social Change143 , pp.336 - 352

Company mergers are complex where several firm-specific and contextual factors interact with each other impacting the outcome of the process. Although many firms merge with or acquire others to increase the value of their firms, have more market power and gain more ability to negotiate with suppliers or customers, most of mergers and acquisitions result in failures. Despite the poor performances, firms continue to merge and acquire. The existing literature on the other hand lacks in providing a robust theory to the issue of poor post-merger performance. This study thus responds to exploring the issue of high failure rates in mergers . . . and acquisitions in an entirely different way. As the first output of a research programme on the conceptual, theoretical and empirical issues in merger and acquisitions research, we conceptualize the loss of performance or exergy in mergers and acquisitions using thermodynamic analysis of the mixing process in physical systems. Three propositions are developed that conceptualize the ideal conditions for mergers in terms of firm size, relatedness between the merging firms and the ambient states. The exergy loss due to merging increases with the increasing levels of strategic or cultural incompatibility between the two firms. When the sizes of two firms differ, it is preferable for the larger firm to have higher knowledge base than the smaller firm. Lastly, the knowledge intensity of the country that the merging takes place as well as the relative knowledge base of the merging firms do interact and change the post-merger performance significantly. © 2018 Elsevier Inc Daha fazlası Daha az

Familial Chiari Type 1: A Molecular Karyotyping Study in a Turkish Family and Review of the Literature

Keser, N. | Kuskucu, A. | Is, M. | Celikoglu, E.

Article | 2019 | World Neurosurgery121 , pp.336 - 352

Background: The etiology of Chiari I malformation (CMI) has not been fully elucidated. Therefore, we performed a genetic study of a Turkish family in which 3 sisters had a diagnosis of CMI with or without syringomyelia. Methods: In a family with 7 children, 4 daughters complained of occipital headaches. In 2 of these daughters, CMI had been diagnosed during their 30s, and CMI plus syrinx had been diagnosed in the other daughter in her 40s. Cranial magnetic resonance imaging of the fourth daughter who had developed headaches during her 30s showed normal findings. Because the other siblings in the family were asymptomatic, radiologica . . .l examinations were not performed. The family had a history of distant consanguineous marriage between parents. Additionally, the father had died, and the mother was asymptomatic, with radiologically normal findings. Array comparative genome hybridization studies were performed for 12 persons from 3 generations of this family. Results: None of the 12 cases examined harbored copy number variations. Conclusions: This family with 3 sisters having CMI suggested a possible autosomal recessive single-gene etiology. Cases of familial CMI are unusual but important to study because they could reveal the specific genes involved in posterior fossa/foramen magnum structure and function and provide insights into the cause of sporadic cases. © 2018 Elsevier Inc Daha fazlası Daha az

Descemet-stripping automated endothelial keratoplasty in eyes with toxic anterior segment syndrome after cataract surgery

Arslan, O.S. | Ünal, M. | Arici, C. | Görgün, E. | Yenerel, M. | Cicik, E.

Article | 2010 | Journal of Cataract and Refractive Surgery36 ( 6 ) , pp.965 - 969

Purpose: To report the results of Descemet-stripping automated endothelial keratoplasty (DSAEK) in eyes with toxic anterior segment syndrome (TASS) after cataract surgery. Setting: Department of Ophthalmology, Istanbul University Cerrahpaşa Medical Faculty, Istanbul, Turkey. Methods: In this prospective study of consecutive patients who had DSAEK for corneal failure due to TASS, the main outcome measures were corneal clarity, mean spherical equivalent (SE) refraction, preoperative and postoperative visual acuities, central corneal thickness, and endothelial cell count (ECC). Results: The mean follow-up in the 10 eyes (10 patients) w . . .as 17.1 months ± 2.4 (SD). There were no graft dislocations postoperatively, and no graft required repositioning. All grafts were clear at 12 months. Two eyes had initial graft rejection that resolved with treatment. All eyes had improved postoperative corrected distance visual acuity, with 7 eyes (70%) attaining 0.5 or better. The mean SE refraction in measurable cases (5 eyes) was 1.2 ± 0.6 preoperatively and 0.9 ± 1.0 postoperatively (P = .141). The decrease in mean pachymetry from preoperatively (691 ± 15 µm) to 12 months postoperatively (614 ± 23 µm) was statistically significant (P = .005). The mean ECC was 2740 ± 236 cells/mm2 preoperatively, 1690 ± 209 cells/mm2 at 6 months, and 1683 ± 206 cells/mm2 at 12 months. The decrease between preoperatively and 6 and 12 months (P = .05) and between 6 months and 12 months (P = .008) was statistically significant. Conclusion: Descemet-stripping automated endothelial keratoplasty was safe and effective in eyes with TASS-associated corneal edema, yielding encouraging surgical and visual outcomes. Financial Disclosure: No author has a financial or proprietary interest in any material or method mentioned. © 2010 ASCRS and ESCRS Daha fazlası Daha az

Phenolipids as New Antioxidants: Production, Activity, and Potential Applications

Kahveci, D. | Laguerre, M. | Villeneuve, P.

Book Part | 2015 | Polar Lipids: Biology, Chemistry, and Technology , pp.185 - 214

Phenolics are secondary metabolites widely found in plants; they have several biological roles and they contribute to the defense system of the host. Among them, the phenolic acid family is one of the most important classes and is mainly composed of the cinnamic and benzoic acid derivatives. The interest in these compounds from a nutritional point of view has risen due to their potential properties, including antioxidant, anti-inflammatory, antiallergic, antimicrobial, antiviral, and anti carcinogenic. As phenolic acids have a rather low solubility in oils, improvement of hydrophopicity of these compounds by chemical or enzymatic li . . .pophilization has been applied extensively to render these functionalized compounds, so-called phenolipids, active in the oil-water interphase. This chapter focuses on the synthesis of phenolipids derived from phenolic acids, their physicochemical and biological activity, and their potential applications. It also discusses the production technology of phenolipids. One of the most reliable methods to improve antioxidant activity of phenolics is to incorporate properly positioned lipophilic groups to obtain phenolipids. Phenolipids show greater miscibility and incorporation into lipid phases and lipocarriers, offering an advantage for their use in drug delivery systems, pharmaceuticals, nutraceuticals, foods, and cosmetic formulations. © 2015 by AOCS Press. All rights reserved Daha fazlası Daha az

A Simplified Formula Discriminating Subtle Anterior Wall Myocardial Infarction from Normal Variant ST-Segment Elevation

Aslanger, E. | Yıldırımtürk, Ö. | Bozbeyoğlu, E. | Şimşek, B. | Karabay, C.Y. | Türer Cabbar, A. | Değertekin, M.

Article | 2018 | American Journal of Cardiology122 ( 8 ) , pp.1303 - 1309

Benign variant (BV) ST-segment elevation (STE) is present in anterior chest leads in most individuals and may cause diagnostic confusion in patients presenting with chest pain. Recently, 2 regression formulas were proposed for differentiation of BV-STE from anterior ST-elevation myocardial infarction (MI) on the electrocardiogram, computation of which is heavily device-dependent. We hypothesized that a simpler visual-assessment-based formula, namely (R-wave amplitude in lead V4 + QRS amplitude in V2) – (QT interval in millimeters + STE60 in V3), will be noninferior to these formulas. Consecutive cases of proven left anterior descend . . .ing occlusion were reviewed, and those with obvious ST elevation MI were excluded. First 200 consecutive patients with noncardiac chest pain and BV-STE were also enrolled as a control group. Relevant electrocardiographic parameters were measured. There were 138 anterior MI and 196 BV-STE cases. Our simple formula was superior to the 3- and noninferior to the 4-variable formulas. This new practical formula had an excellent area-under curve of 0.963 (95% confidence interval, 0.946 to 0.980, Daha fazlası Daha az

Ionic Liquids in Acylglycerol Synthesis and Modification

Kahveci, D. | Zhong, N. | Xu, X.

Book Part | 2016 | Ionic Liquids in Lipid Processing and Analysis: Opportunities and Challenges , pp.251 - 278

Acylglycerols, which are the esters between glycerol and free fatty acids, include monoacylglycerols (MAG), diacylglycerols (DAG), and triacylglycerols (TAG). Natural oils and fats are primarily composed of TAG (more than 95% in general). Therefore, the processing manipulation of oils and fats to produce MAG and DAG has been the target in studies as well as in industry. There are synthetic studies or industrial practice to produce TAG from different materials. The use of ionic liquids (ILs) in TAG synthesis has not received substantial attention. This chapter is focused on the MAG and DAG. Attention has been given to the enzyme-cata . . .lyzed processes in this chapter, where ILs play a special role in the reaction system for the formation of MAG and DAG. © 2016 Copyright © 2016 AOCS Press Published by Elsevier Inc. All rights reserved Daha fazlası Daha az

Predictors of success during the coasting period in high-responder patients undergoing controlled ovarian stimulation for assisted conception

Ulug, U. | Ben-Shlomo, I. | Bahceci, M.

Article | 2004 | Fertility and Sterility82 ( 2 ) , pp.338 - 342

Objective To determine the prognostic factors analyzed during the coasting period that can be used to predict outcomes of IVF cycles. Design Retrospective review of data from a single center. Setting Referral private IVF center. Patient(s) Three hundred forty-six patients who were coasted for the prevention of ovarian hyperstimulation syndrome (OHSS) and 262 patients who were not coasted but having excessive E2 levels during controlled ovarian hyperstimulation for assisted conception. Intervention(s) Controlled ovarian hyperstimulation, oocyte retrieval, intracytoplasmic sperm injection, and embryo transfer. Main outcome measure(s) . . .Number of total oocytes retrieved, oocyte maturity, fertilization, implantation and pregnancy rates (IR and PR, respectively), and incidence of severe OHSS. Result(s) No difference was found between early onset coasted patients, late onset coasted patients, and uncoasted patients in terms of fertilization rates, IR, PR, and incidence of severe OHSS. Fertilization and PR did not correlate significantly with decreases in E 2 level during the coasting period. Implantation rates and PR in patients who were coasted ?4 days were significantly reduced compared with patients who were coasted for 1-3 days. In logistic regression model, the decrease in PR with prolonged coasting was found to be significant; however, there was no correlation between decreased PR and the decrease in E2 levels during the coasting period. Conclusion(s) Coasting can be applied safely to controlled hyperstimulation cycles without compromising the outcome. The duration of coasting seems to be a prognostic factor for the outcome of IVF. The criteria for initiation of coasting should be based on clinical experience and assessment of the patient. © 2004 by American Society for Reproductive Medicine Daha fazlası Daha az

Parallel Implicit Solution of 3-D Navier-Stokes Equations

Gülçat, Ü. | Ünal, V.Ü.

Book Part | 2003 | Parallel Computational Fluid Dynamics 2002: New Frontiers and Multi-Disciplinary Applications , pp.281 - 288

Parallel implicit solution of Navier-Stokes equations based on two fractional steps in time and Finite Element discretization in space is presented. The accuracy of the scheme is second order in both time and space domains. Large time step sizes, with CFL numbers much larger than unity, are used. The Domain Decomposition Technique is implemented for parallel solution of the problem with matching and non-overlapping sub domains. Lid-driven flow in a cubic cavity with Reynolds number of 400 and 1000 is selected as a test case. The solution domain is divided into 2, 4 and 6 sub-domains. Time accurate solutions are obtained with time st . . .eps 5 times the step size of a stable explicit method. Super-linear speed-up is achieved with the modified Domain Decomposition Technique. © 2003 Elsevier B.V. All rights reserved Daha fazlası Daha az

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