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Zero valent zinc nanoparticles promote neuroglial cell proliferation: A biodegradable and conductive filler candidate for nerve regeneration

Aydemir Sezer, U. | Ozturk, K. | Aru, B. | Yanıkkaya Demirel, G. | Sezer, S. | Bozkurt, M.R.

Article | 2017 | Journal of Materials Science: Materials in Medicine28 ( 1 )

Regeneration of nerve, which has limited ability to undergo self-healing, is one of the most challenging areas in the field of tissue engineering. Regarding materials used in neuroregeneration, there is a recent trend toward electrically conductive materials. It has been emphasized that the capacity of conductive materials to regenerate such tissue having limited self-healing ability improves their clinical utility. However, there have been concerns about the safety of materials or fillers used for conductance due to their lack of degradability. Here, we attempt to use poly(?-caprolactone) (PCL) matrix consisting of varying proporti . . .ons of zero valent zinc nanoparticles (Zn NPs) via electrospinning. These conductive, biodegradable, and bioactive materials efficiently promoted neuroglial cell proliferation depending on the amount of Zn NPs present in the PCL matrix. Chemical characterizations indicated that the incorporated Zn NPs do not interact with the PCL matrix chemically and that the Zn NPs improved the tensile properties of the PCL matrix. All composites exhibited linear conductivity under in vitro conditions. In vitro cell culture studies were performed to determine the cytotoxicity and proliferative efficiency of materials containing different proportions of Zn NPs. The results were obtained to explore new conductive fillers that can promote tissue regeneration. © 2016, Springer Science+Business Media New York Daha fazlası Daha az

Productivity and technical change in Malaysian banking: 1989-1998

E. Dogan | D.K. Fausten

Article | 2003 | Asia-Pacific Financial Markets10 ( 02.03.2020 ) , pp.205 - 237

This study examines the impact of deregulation and technological change on the productivity of Malaysian banks over the period 1989-1998. Malmquist indices constructed with nonparametric DEA techniques are decomposed into their pure efficiency, scale efficiency, and technological change components. Our findings indicate an erosion of banking productivity that masks divergent tendencies among its component elements. These are dominated by adverse effects of technological change, which are associated with a reduction in the labor intensity of banking activity. Consistent with the mixed findings reported in the literature, the present . . .investigation suggests that regulatory reform and liberalization are not sufficient conditions for productivity improvement. © Springer 2005 Daha fazlası Daha az

A Review on protein-protein interaction network databases

Pedamallu, C.S. | Ozdamar, L.

Conference Object | 2014 | Springer Proceedings in Mathematics and Statistics73 , pp.511 - 519

International Conference on Modeling, Optimization and Dynamics, ICMOD 2010 and 5th Bioeconomy Conference 2012 -- 5 July 2010 through 7 July 2010 -- -- 117169

On the use of cross impact analysis for enhancing performance in primary school education

Pedamallu, C.S. | Ozdamar, L. | Weber, G.-W.

Conference Object | 2014 | Springer Proceedings in Mathematics and Statistics73 , pp.521 - 538

International Conference on Modeling, Optimization and Dynamics, ICMOD 2010 and 5th Bioeconomy Conference 2012 -- 5 July 2010 through 7 July 2010 -- -- 117169

Development of a system for temperature profile characterization of baths

Torun, M.K. | İnce, A.T.

Article | 2011 | International Journal of Thermophysics32 ( 11.12.2020 ) , pp.2370 - 2378

Liquid baths are the main calibration equipment to directly affect the measurement uncertainty in temperature calibrations. Therefore, the characteristics of baths need to be well investigated and understood. The temperature profile and stability of liquid baths are one of the most important contributions to the calibration uncertainty of platinum resistance thermometers, digital thermometers, liquid-in-glass thermometers, and thermocouples. Commercial baths only present stability and uniformity data in two dimensions in general; however, thermometers and thermocouples are immersed into the body of the bath, so the depth or z-axis i . . .s also very important. In this study, a measurement system has been designed using three-stepper motors and a data acquisition system (DAS). The DAS is developed using object-oriented algorithms to form a three-dimensional (3-D) scanning system. The 3-D scanning system is home-made and used in conjunction with a reference platinum thermometer. The temperature profiles and stability of several types of baths: water, oil, and salt were obtained in the temperature range from 30°C to 450°C. Therefore, this contributed toward a more accurate uncertainty budget evaluation. © 2011 Springer Science+Business Media, LLC Daha fazlası Daha az

Bronchial Artery Embolization with Large Sized (700–900 µm) Tris-acryl Microspheres (Embosphere) for Massive Hemoptysis: Long-Term Results (Clinical Research)

Kucukay, F. | Topcuoglu, O.M. | Alpar, A. | Altay, Ç.M. | Kucukay, M.B. | Ozbulbul, N.I.

Article | 2018 | CardioVascular and Interventional Radiology41 ( 2 ) , pp.225 - 230

Purpose: To investigate the safety, efficacy and long-term results of bronchial artery embolization with microsphere particles (Embosphere® Microspheres, BioSphere Medical, Rockland, MA) 700–900 µm in size for massive hemoptysis. Methods: One hundred and seventy-four patients (94 female, 80 male; mean age 39.4 ± 5.7) who had bronchial artery embolization for massive hemoptysis between January 2010 and October 2015 were incorporated in the study. Patients had hemoptysis with a mean volume of 525 ± 150 mL (median 500 mL, range 300–1200 mL) over a 24-h period. Underlying pathologies included bronchial artery hypertrophy due to bronchie . . .ctasis (56.3% [98/174]), lung cancer (29.9% [52/174]), tuberculosis (10.3% [18/174]) and the rest remained idiopathic (3.4% [6/174]). Mean bronchial artery diameter before the intervention was 3.8 ± 1.5 mm (median 4 mm, range 3.1–7.5 mm). Median follow-up period was 56 months (range 10–82 months). Primary objectives were the technical and clinical success. Results: Technical success was 100%. Clinical success for preventing massive hemoptysis was 91.9% (160/174). There was no procedure-related mortality or morbidities. Minor complications such as chest pain were observed in nine patients (5.0%). Recurrent hemoptysis (8.1%) was observed within 6 months in 14 patients, ten of whom were treated with a second embolization session and the remaining four with a total of three embolization sessions. Conclusion: Bronchial artery embolization for massive hemoptysis with Embosphere particles 700–900 µm in size is a safe and effective method with high technical and clinical success rates. Long-term results are excellent. © 2017, Springer Science+Business Media, LLC and the Cardiovascular and Interventional Radiological Society of Europe (CIRSE) Daha fazlası Daha az

The role of weak links and Zn-doping on magnetic parameters of high-T c superconductors

Topal, U. | Coker, E.G. | Alıkma, F. | Kolemen, U. | Uzun, O.

Article | 2014 | Journal of Superconductivity and Novel Magnetism27 ( 1 ) , pp.133 - 141

The second harmonic signal, which is generated by co-application of AC and DC fields to polycrystalline type-II superconductors, were analyzed in terms of the weak links and the critical current density. With this aim the YBa 2 Cu 3-x Zn x O 7-y (x=0, 0.01, 0.02, 0.03, 0.05, and 0.1) samples were synthesized in order to adjust intergranular couplings and thus the strength of weak links. The mechanical and magnetic measurements are in good agreement on that Zn doping reduces strength of the links between grains; however, contrary to the common expectations, it has no direct contribution to the 2nd harmonic signal strength. © 2013 Spr . . .inger Science+Business Media New York Daha fazlası Daha az

Videolization: knowledge graph based automated video generation from web content

Kalender, M. | Eren, M.T. | Wu, Z. | Cirakman, O. | Kutluk, S. | Gultekin, G. | Korkmaz, E.E.

Article | 2018 | Multimedia Tools and Applications77 ( 1 ) , pp.567 - 595

Web content nowadays can also be accessed through new generation of Internet connected TVs. However, these products failed to change users’ behavior when consuming online content. Users still prefer personal computers to access Web content. Certainly, most of the online content is still designed to be accessed by personal computers or mobile devices. In order to overcome the usability problem of Web content consumption on TVs, this paper presents a knowledge graph based video generation system that automatically converts textual Web content into videos using semantic Web and computer graphics based technologies. As a use case, Wikip . . .edia articles are automatically converted into videos. The effectiveness of the proposed system is validated empirically via opinion surveys. Fifty percent of survey users indicated that they found generated videos enjoyable and 42 % of them indicated that they would like to use our system to consume Web content on their TVs. © 2016, Springer Science+Business Media New York Daha fazlası Daha az

Neuroendocrine responses to traumatic brain injury

Kelestimur, F.

Editorial | 2019 | Pituitary22 ( 3 ) , pp.199 - 200

[No abstract available]

A decomposition approach for the home health care problem with time windows

Yalçındağ, S. | Matta, A.

Conference Object | 2017 | Springer Proceedings in Mathematics and Statistics210 , pp.221 - 232

Optimization tools are necessary to efficiently plan service delivery for patients at home in the context of Home Health Care services. In the scientific literature, Periodic Vehicle Routing Problem with Time Windows (PVRPTW) is proposed to address the assignment, scheduling and routing processes with time windows. However, PVRPTW is computationally difficult and not viable for large-size problems. Thus, a practical approach is proposed to decompose the problem. Time windows are considered at the assignment level using a probabilistic model without the need of solving the routing problem. Mixed integer mathematical programming model . . .s are proposed and solved by CPLEX solver. Numerical experiments are executed to validate the performance of the proposed models with respect to the PVRPTW. © Springer International Publishing AG 2017 Daha fazlası Daha az

Does Primary Hyperparathyroidism Have an Association with Thyroid Papillary Cancer? A Retrospective Cohort Study

Çetin, K. | Sıkar, H.E. | Temizkan, Ş. | Ofluoğlu, C.B. | Özderya, A. | Aydın, K. | Küçük, H.F.

Article | 2019 | World Journal of Surgery43 ( 5 ) , pp.1243 - 1248

Background: To investigate the relationship between primary hyperparathyroidism (pHPT) and papillary thyroid cancer (PTC). Methods: The perioperative findings of 275 patients with pHPT who underwent surgery between January 2014 and December 2017 were retrospectively reviewed. Thirty-one patients were diagnosed with pHPT and PTC concurrently. Pathology results and demographic findings of these patients were compared with 186 patients who underwent thyroidectomy and diagnosed with PTC at the same time interval. Results: The co-occurrence of pHPT and PTC was 11.3% (31/275). The median ages of the pHPT, pHPT + PTC, and PTC groups were 5 . . .5, 57, and 50 years old, respectively (p < 0.001). The diameter of tumor was smaller in the pHPT + PTC group [median 7 mm (range 0.5–25 mm) vs. 15 mm (range 1–100 mm)], with higher rates of microcarcinomas (p < 0.001), than the patients in the PTC group. Examination of tumor morphology showed higher rates of tumor capsule invasion and multicentricity in the pHPT + PTC group than those in the isolated PTC group (p = 0.02, p = 0.04, respectively). Conclusion: The pHPT + PTC group had significantly smaller tumor diameter than the PTC group. This result may support the idea that pHPT leads to overdiagnosis of PTC. However, observation of high rates of tumor capsule invasion and multicentricity in the pHPT + PTC group may suggest an associative etiology with more aggressive PTC. © 2019, Société Internationale de Chirurgie Daha fazlası Daha az

Memetic algorithms for parallel code optimization

Özcan, E. | Onbaşioğlu, E.

Article | 2007 | International Journal of Parallel Programming35 ( 1 ) , pp.33 - 61

Discovering the optimum number of processors and the distribution of data on distributed memory parallel computers for a given algorithm is a demanding task. A memetic algorithm (MA) is proposed here to find the best number of processors and the best data distribution method to be used for each stage of a parallel program. Steady state memetic algorithm is compared with transgenerational memetic algorithm using different crossover operators and hill-climbing methods. A self-adaptive MA is also implemented, based on a multimeme strategy. All the experiments are carried out on computationally intensive, communication intensive, and mi . . .xed problem instances. The MA performs successfully for the illustrative problem instances. © Springer Science+Business Media, LLC 2007 Daha fazlası Daha az

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