Gürses, B. | Kabakci, N. | Kovanlikaya, A. | Firat, Z. | Bayram, A. | Ulug, A.M. | Kovanlikaya, I.
Erratum | 2008 | European Radiology18 ( 4 )
[No abstract available]
Gürses, B. | Kabakci, N. | Kovanlikaya, A. | Firat, Z. | Bayram, A. | Uluo, A.M. | Kovanlikaya, I.
Article | 2008 | European Radiology18 ( 4 ) , pp.716 - 721
The aim of this study was to assess the feasibility of diffusion tensor imaging (DTI) of the prostate and to determine normative fractional anisotropy (FA) and apparent diffusion coefficient (ADC) values of healthy prostate with a 3-Tesla magnetic resonance imaging (MRI) system. Thirty volunteers with a mean age of 28 (25-35) years were scanned with a 3-Tesla MRI (Intera Achieva; Philips, The Netherlands) system using a six-channel phased array coil. Initially, T2-weighted turbo spin-echo (TSE) axial images of the prostate were obtained. In two subjects, a millimetric hypointense signal change was detected in the peripheral zones on . . . T2-weighted TSE images. These two subjects were excluded from the study. DTI with single-shot echo-planar imaging (ssEPI) was performed in the remaining 28 subjects. ADC and FA values were measured using the manufacturer supplied software by positioning 9-pixel ROIs on each zone. Differences between parameters of the central and peripheral zones were assessed. Mean ADC value of the central (1.220±0.271 × 10-3 mm2/s) was found to be significantly lower when compared with the peripheral gland (1.610±0.347 × 10-3 mm2/s) (P<0.01). Mean FA of the central gland was significantly higher (0.26), compared with the peripheral gland (0.16) (P<0.01). This study shows the feasibility of prostate DTI with a 3-Tesla MR system and the normative FA and ADC values of peripheral and central zones of the normal prostate. The results are compatible with the microstructural organization of the gland. © European Society of Radiology 2007 Daha fazlası Daha az
Inci, E. | Kilickesmez, O. | Hocaoglu, E. | Aydin, S. | Bayramoglu, S. | Cimilli, T.
Article | 2011 | European Radiology21 ( 4 ) , pp.768 - 775
Objectives: To evaluate the value of diffusion-weighted MRI (DWI) in the diagnosis of acute appendicitis. Methods: 119 patients with acute appendicitis and 50 controls were enrolled in this prospective study. DWI was obtained with b factors 0, 500 and 1000 s/mm2 and were assessed with a visual scoring system by two radiologists followed by quantitative evaluation of the DW images and ADC maps. Results: Histopathology revealed appendicitis in 79/92 patients (78%) who had undergone surgery. On visual evaluation, except for one patient with histopathologically proven appendicitis all inflamed appendixes were hyperintense on DWI (98.7%) . . .. Quantitative evaluation with DW signal intensities and ADC values revealed a significant difference with normal and inflamed appendixes (p < 0.001). The best discriminative parameter was signal intensity (b 500). With a cut-off value of 56 for the signal intensity the ratio had a sensitivity of 99% and a specificity of 97%. The cut-off ADC value at 1.66 mm2/s had a sensitivity of 97% and a specificity of 99%. Conclusion: DWI is a valuable technique for the diagnosis of acute appendicitis with both qualitative and quantitative evaluation. DWI increases the conspicuity of the inflamed appendix. We recommend using DWI to diagnose acute appendicitis. © 2010 European Society of Radiology Daha fazlası Daha az