Personalized evaluation of oxygen and carbon dioxide exchange in Covid-19 patients with regard to energy homeostasis

  • Yazar [KatkıdaBulunan] Temur, Sibel
    Ercan, Sina
    Akduman, Seha
    Gücü, Ecem
    Erdoğan, Cihan Süleyman
    Yenikale, Ayberk
    Özilgen, Mustafa
  • Yayın Turu [Akademik] Preprint
  • Yayın Tarihi 2021
  • Yayıncı Yeditepe University Academic and Open Access Information System
  • Tek Biçim Adres https://hdl.handle.net/20.500.11831/7958

The COVID-19 does not proceed the same way in every patient. It may interfere with both oxygen (O2) and carbon dioxide (CO2) exchange in the alveoli; therefore, prevent ATP generation; subsequently, restrict energy supply for the life processes of the patient. Data sets representing the course of the COVID-19 in four patients, where the disease followed dissimilar paths were reassessed after the end of the treatment, by focusing on the respiratory and metabolic energy related parameters (FiO2, PaO2, SaO2, PaCO2) and the other parameters such as HCO3, lactate, body temperature, C-reactive protein (CRP) and blood urea nitrogen levels. The valuable treatment data pertinent to each individual showed that each of them needed a personal treatment method. Group based statistical analyses may cause loss of the valuable medical information, if some of the dissimilar treatment details is considered as outliers. NIH has very recently reported that, there is no sufficient data yet to recommend either for or against the use of extracorporeal membrane oxygenation (ECMO) in the treatment of the COVID-19 patients. However, the results of this study suggest that ECMO may be useful for removal of the CO2 from some of the COVID-19 patients; therefore, will be helpful if used in their treatment.

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treatment COVID-19 patients valuable dissimilar therefore parameters energy patient method information medical analyses statistical oxygenation removal needed helpful showed individual pertinent personal details useful membrane extracorporeal against However either results recommend sufficient (ECMO) reported recently
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Eser AdıPersonalized evaluation of oxygen and carbon dioxide exchange in Covid-19 patients with regard to energy homeostasis
Yazar [Asıl]Yılmaz, Bayram
Yazar DepartmanıYeditepe Üniversitesi Tıp Fakültesi Fizyoloji Bölümü
Yazar Orcid0000-0002-2674-6535
Yayın Tarihi2021
Yayın Turu [Akademik]preprint
Yayın Türü [Ortam]application/pdf
Konu Başlıkları [Genel]COVID-19
Konu Başlıkları [Genel]ECMO
Konu Başlıkları [Genel]Energy metabolism
Konu Başlıkları [Genel]Extracorporeal methods
Konu Başlıkları [Genel]Oxygen and carbon dioxide exchange
Konu Başlıkları [Genel]Pneumonia
YayıncıYeditepe University Academic and Open Access Information System
Dileng
Özet BilgisiThe COVID-19 does not proceed the same way in every patient. It may interfere with both oxygen (O2) and carbon dioxide (CO2) exchange in the alveoli; therefore, prevent ATP generation; subsequently, restrict energy supply for the life processes of the patient. Data sets representing the course of the COVID-19 in four patients, where the disease followed dissimilar paths were reassessed after the end of the treatment, by focusing on the respiratory and metabolic energy related parameters (FiO2, PaO2, SaO2, PaCO2) and the other parameters such as HCO3, lactate, body temperature, C-reactive protein (CRP) and blood urea nitrogen levels. The valuable treatment data pertinent to each individual showed that each of them needed a personal treatment method. Group based statistical analyses may cause loss of the valuable medical information, if some of the dissimilar treatment details is considered as outliers. NIH has very recently reported that, there is no sufficient data yet to recommend either for or against the use of extracorporeal membrane oxygenation (ECMO) in the treatment of the COVID-19 patients. However, the results of this study suggest that ECMO may be useful for removal of the CO2 from some of the COVID-19 patients; therefore, will be helpful if used in their treatment.
Kayıt Giriş Tarihi2021-09-04
Açık Erişim Tarihi2021-09-04
HaklarYeditepe University Academic and Open Access Information System
Erişim HakkıOpen Access
Telif HakkıUnless otherwise stated, copyrights belong to Yeditepe University. Usage permissions are specified in the Open Access System, and "InC-NC/1.0" and "by-nc-nd/4.0" are as stated.
Telif Hakkı Urlhttp://creativecommons.org/licenses/by-nc-nd/4.0
Telif Hakkı Urlhttps://rightsstatements.org/page/InC-NC/1.0/?language=en
Açıklama [Genel]Final published version
Açıklama [Not]Note: This preprint reports new research that has not been certified by peer review and should not be used as established information without consulting multiple experts in the field.
Tanım Koleksiyon BilgisiThis item is part of the preprint collection made available through Yeditepe University library. For your questions, our contact address is openaccess@yeditepe.edu.tr
Yazar [KatkıdaBulunan]Temur, Sibel
Yazar [KatkıdaBulunan]Ercan, Sina
Yazar [KatkıdaBulunan]Akduman, Seha
Yazar [KatkıdaBulunan]Gücü, Ecem
Yazar [KatkıdaBulunan]Erdoğan, Cihan Süleyman
Yazar [KatkıdaBulunan]Yenikale, Ayberk
Yazar [KatkıdaBulunan]Özilgen, Mustafa
Yazar [KatkıdaBulunan] KurumYeditepe University Faculty of Medicine
Tek Biçim Adreshttps://hdl.handle.net/20.500.11831/7958
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