The COVID-19 does not proceed the same way in every patient. It may interfere with both oxygen (O2) and carbon dioxide (CO2) exchange in the alveoli; therefore, prevent ATP generation; subsequently, restrict energy supply for the life processes of the patient. Data sets representing the course of the COVID-19 in four patients, where the disease followed dissimilar paths were reassessed after the end of the treatment, by focusing on the respiratory and metabolic energy related parameters (FiO2, PaO2, SaO2, PaCO2) and the other parameters such as HCO3, lactate, body temperature, C-reactive protein (CRP) and blood urea nitrogen levels. The valuable treatment data pertinent to each individual showed that each of them needed a personal treatment method. Group based statistical analyses may cause loss of the valuable medical information, if some of the dissimilar treatment details is considered as outliers. NIH has very recently reported that, there is no sufficient data yet to recommend either for or against the use of extracorporeal membrane oxygenation (ECMO) in the treatment of the COVID-19 patients. However, the results of this study suggest that ECMO may be useful for removal of the CO2 from some of the COVID-19 patients; therefore, will be helpful if used in their treatment.
Title (dc.title) | Personalized evaluation of oxygen and carbon dioxide exchange in Covid-19 patients with regard to energy homeostasis |
Author [Asıl] (dc.creator.author) | Yılmaz, Bayram |
Yazar Departmanı (dc.creator.department) | Yeditepe Üniversitesi Tıp Fakültesi Fizyoloji Bölümü |
Author Orcid (dc.creator.orcid) | 0000-0002-2674-6535 |
Publication Date (dc.date.issued) | 2021 |
Publication Type [Academic] (dc.type) | preprint |
Publication Type [Media] (dc.format) | application/pdf |
Subject Headings [General] (dc.subject) | COVID-19 |
Subject Headings [General] (dc.subject) | ECMO |
Subject Headings [General] (dc.subject) | Energy metabolism |
Subject Headings [General] (dc.subject) | Extracorporeal methods |
Subject Headings [General] (dc.subject) | Oxygen and carbon dioxide exchange |
Subject Headings [General] (dc.subject) | Pneumonia |
Publisher (dc.publisher) | Yeditepe University Academic and Open Access Information System |
Language (dc.language.iso) | eng |
Abstract (dc.description.abstract) | The COVID-19 does not proceed the same way in every patient. It may interfere with both oxygen (O2) and carbon dioxide (CO2) exchange in the alveoli; therefore, prevent ATP generation; subsequently, restrict energy supply for the life processes of the patient. Data sets representing the course of the COVID-19 in four patients, where the disease followed dissimilar paths were reassessed after the end of the treatment, by focusing on the respiratory and metabolic energy related parameters (FiO2, PaO2, SaO2, PaCO2) and the other parameters such as HCO3, lactate, body temperature, C-reactive protein (CRP) and blood urea nitrogen levels. The valuable treatment data pertinent to each individual showed that each of them needed a personal treatment method. Group based statistical analyses may cause loss of the valuable medical information, if some of the dissimilar treatment details is considered as outliers. NIH has very recently reported that, there is no sufficient data yet to recommend either for or against the use of extracorporeal membrane oxygenation (ECMO) in the treatment of the COVID-19 patients. However, the results of this study suggest that ECMO may be useful for removal of the CO2 from some of the COVID-19 patients; therefore, will be helpful if used in their treatment. |
Record Add Date (dc.date.accessioned) | 2021-09-04 |
Açık Erişim Tarihi (dc.date.available) | 2021-09-04 |
Haklar (dc.rights) | Yeditepe University Academic and Open Access Information System |
Erişim Hakkı (dc.rights.access) | Open Access |
Copyright (dc.rights.holder) | Unless otherwise stated, copyrights belong to Yeditepe University. Usage permissions are specified in the Open Access System, and "InC-NC/1.0" and "by-nc-nd/4.0" are as stated. |
Copyright Url (dc.rights.uri) | http://creativecommons.org/licenses/by-nc-nd/4.0 |
Copyright Url (dc.rights.uri) | https://rightsstatements.org/page/InC-NC/1.0/?language=en |
Description (dc.description) | Final published version |
Description [Note] (dc.description.note) | Note: This preprint reports new research that has not been certified by peer review and should not be used as established information without consulting multiple experts in the field. |
Description Collection Information (dc.description.collectioninformation) | This item is part of the preprint collection made available through Yeditepe University library. For your questions, our contact address is openaccess@yeditepe.edu.tr |
Yazar [KatkıdaBulunan] (dc.contributor.author) | Temur, Sibel |
Yazar [KatkıdaBulunan] (dc.contributor.author) | Ercan, Sina |
Yazar [KatkıdaBulunan] (dc.contributor.author) | Akduman, Seha |
Yazar [KatkıdaBulunan] (dc.contributor.author) | Gücü, Ecem |
Yazar [KatkıdaBulunan] (dc.contributor.author) | Erdoğan, Cihan Süleyman |
Yazar [KatkıdaBulunan] (dc.contributor.author) | Yenikale, Ayberk |
Yazar [KatkıdaBulunan] (dc.contributor.author) | Özilgen, Mustafa |
Author [Contributor] Institution (dc.contributor.institution) | Yeditepe University Faculty of Medicine |
Single Format Address (dc.identifier.uri) | https://hdl.handle.net/20.500.11831/7958 |