Norepinephrine (NE) is a well-known appetite regulator, and the nor/adrenergic system is targeted by several anti-obesity drugs. To better understand the circuitry underlying adrenergic appetite control, here we investigated the paraventricular hypothalamic nucleus (PVN), a key brain region that integrates energy signals and receives dense nor/adrenergic input, using a mouse model. We found that PVN NE level increases with signals of energy deficit and decreases with food access. This pattern is recapitulated by the innervating catecholaminergic axon terminals originating from NTSTH-neurons. O ...Daha fazlası
The last decade has seen an increase in Hollywood productions of cyberpunk films. These films, designed as remakes or sequels, appeal to both old fans of the cult original films and new audiences. The subject of this research is how the remakes, which aim to guarantee the box office undergo changes and how they fit into the system compared to the originals. In the research, it has been attempted to reveal how these change narratives have been integrated into current policies and the system compared to the originals, and to determine and show in which contexts this transformation of the remakes ...Daha fazlası
The usage of the Internet in our daily life, the unstoppable development of technology and competition have made it necessary for financial institutions to work more technology oriented. Because banks have turned to digital banking applications. By using digital tools, people can to most of the things automated and faster that they have done manually in the past and ubiquitous mobile technologies introduced more opportunities for digital life style. In the context of COVID-19 consumers’ spending and banking preferences are rapidly evolving and retail banks face an urgent imperative to reshape ...Daha fazlası
This thesis argues that there is a symbiotic relationship between the actions of characters making use of different aspects of power, and the plot progression in three tragedies by William Shakespeare; Hamlet, King Lear, and Macbeth, whose plots were built upon a problem of succession. For this purpose, the Aristotelian definition of tragedy was used in conjunction with the notion of power as defined by Steven Lukes throughout the study. To identify how this interaction helps build the dramatic structure, Thomas Pavel’s concept of move was utilised to pinpoint the plot progressionin the three ...Daha fazlası
The phenomenon of international immigration has been one of the important issues both at the international and local level for many years. In Europe, especially after the Second World War, immigration has become a controversial issue in international politics. After the Second World War, while immigration was considered necessary to improve the deteriorating economy of Europe, after the 1970s, immigration began to be limited and border controls were strengthened. This can be clearly seen in the immigration policies developed by the European Union. In 2015, Europe faced a serious immigration cr ...Daha fazlası
The research is designed to examine the essence and roots of Ukrainian nationalism of Western Ukraine, categories of identity regarding Ukrainians, and to present how modern Ukrainian national identity is constructed. The aim of the study is to understand within the broad context of nationalism the complexity of Ukrainian nationalism that does not fit the commonly used definition of a nation; common language, common religion, and common historical memory. The anthropological fieldwork is based on participant observation and in total 35 in-depth interviews which were conducted mainly in Lviv be ...Daha fazlası
This study is important in terms of contextualizing the scattered dissident voices that have developed in the Turkish geography, regardless of genre, within a broad perspective. It offers an uncommon combination of texts on music, art, social sciences, etc. Most of the studies on music to date have not touched upon the Unkapanı record stores bazaar. In this study, Unkapanı İMÇ (Istanbul ManifaturacılarÇarşısı)'s organizations from its first establishment until the time it lost its popularity, communication tools such as radio, cinema, TV used in the spread of popular music, the formation of Un ...Daha fazlası
In the business world of the century we are living in, competition has become quite intense with the effect of globalization. For this purpose; the enterprises started to adopt the "Kaizen" methodology, which means continuous betterment or continuous improvement. Businesses that aspire to be successful and survive for a long time in this competitive environment have to use their resources most efficiently, specialize by gaining experience in their activities, and make strategic planning for the future. Information, being a strategic power, is the most important of these resources. If we consid ...Daha fazlası
Video games depict various fantastic scenarios that players engage in. Fantasy has been a point of interest for humans for much of recorded history and fantasy fulfilment isan important appeal for people to play video games. The experience of such a fantasy can significantly enhance the player’s experience in games. Players experience fantasy in games through its elements:Culmination of gameplay, narrative story and the design of protagonist character(s) are how this fantasy is relayed to the player. The design of these three parts is significant in shaping the player’s fantasy and overall exp ...Daha fazlası
The purpose of this study is to conduct a comprehensive analysis by identifying the formal similarities and functional differences between “Tronie” painting and portrait painting that emerged in Dutch Golden Age painting of the XVII century. The aspects of Tronie painting that deviate from the standard understanding of portraiture are not easy to determine, as it has broad significance in its own genre. It has been misinterpreted by scholars due to the stylistic similarities it exhibits in research, and the form-content structure has been analyzed and clarified with recent studies. Our study h ...Daha fazlası
The emergence of virtual reality in recent years has primarily focused on user interfaces, visual simulation, and 3D graphics. However, the community's interest in virtual reality has shifted towards the gaming industry in order to reach a larger audience. This thesis aims to study the differences and similarities between virtual games and traditional video games in order to determine user preferences and opinions. Over 60 days (April 1st - May 31st, 2023), an online survey gathered 300 comprehensive responses, revealing substantial insights, and 4 interviews have been conducted with 4 volunte ...Daha fazlası
Brain drain, which is defined as the departure of well-educated human capital to another geography, was noticed by England, which lost its qualified power to other countries in 1945 and increased rapidly after the 1960s with the effect of globalization. Countries such as the USA, UK and Germany have developed important brain drain policies from a push and pull perspective. Turkey has also developed important policies such as university reforms. In the following periods, within the scope of Five-Year Development Planning, although TÜBİTAK 2232 developed policies to pull reverse brain drain and ...Daha fazlası
6698 sayılı Kişisel Verilerin Korunması Kanunu kapsamında yükümlülüklerimiz ve çerez politikamız hakkında bilgi sahibi olmak için alttaki bağlantıyı kullanabilirsiniz.