Korachi, M | Ceran, N | Adaleti, R | Nigdelioglu, A | Sokmen, M
Article | 2013 | INTERNATIONAL JOURNAL OF INFECTIOUS DISEASES17 ( 1 )
Background: Investigational approaches based on genome-wide association studies have proven useful in identifying genetic predictors for many diseases, including susceptibility to chronic hepatitis B and C. In these studies, the majority of genetic variants that have shown a positive association have been identified in genes involved in the immune response. In this study IFN-gamma, IFNGR-1, and IRF-1 genes were analyzed for their role in susceptibility to the development of chronic hepatitis B and chronic hepatitis C in a Turkish population. Methods: Polymorphic genes IRF-1 (-410, -388), IFNGR-1 (-56, -611), and IFN-gamma (+874) wer . . .e analyzed in a total of 400 individuals: 100 chronic hepatitis B patients, 100 hepatitis B carriers, 100 chronic hepatitis C patients, and 100 healthy controls. A single base primer extension assay was used. Correlations between genes and gender, viral load, and aspartate aminotransferase (AST) and alanine aminotransferase (ALT) levels were also investigated. Results: The IRF-1 gene at positions -388 and -410 were observed to be candidate gene markers for susceptibility to the development of chronic hepatitis B and C (p < 0.05). IFN-gamma +874 and IFNGR-1 (-56 and -611) correlated with chronic hepatitis B but not chronic hepatitis C. Correlation of functional genotype with viral load and AST and ALT levels revealed an association of IFN-gamma +874 and IFNGR-1 -611 with chronic hepatitis C and IFN-gamma +874 with viral load and chronic hepatitis B (p < 0.05). Conclusions: Findings suggest that IFN-gamma (+874), IRF-1 (-410, -388), and IFNGR-1 (-56, -611) are candidate gene markers for determining patient susceptibility to the development of chronic hepatitis B and C. (C) 2012 International Society for Infectious Diseases. Published by Elsevier Ltd. All rights reserved Daha fazlası Daha az
Karamustafalioglu, N. | Kalelioglu, T. | Tanriover, O. | Gungor, F.C. | Genc, A. | Ilnem, C.
Article | 2013 | Psychiatry Investigation10 ( 4 ) , pp.425 - 427
Priapism is defined as having prolonged (more than 6 h), and usually painful penile erection that occurs without a sexual desire or arousal. Only a very few priapism cases caused by ziprasidone are reported in the literature. In this case report we aimed to present a prolonged penile erection due to use of ziprasidone. © 2013 Korean Neuropsychiatric Association.
P. Kizilirmak | M. Berktas | Y. Uresin | O.B. Yildiz
Article | 2013 | Journal of Clinical Hypertension15 ( 3 ) , pp.193 - 200
Many hypertensive patients require ?2 drugs to achieve blood pressure targets. This study aims to review and analyze the clinical studies conducted with dual or triple combination of angiotensin II receptor blockers (ARBs), calcium channel blockers (CCBs), and diuretics. Medical literature between January 1990 and April 2012 was reviewed systematically and data from eligible studies were abstracted. Data were analyzed using random-effects models. Of the 224 studies screened, 7563 eligible patients from 11 studies were included. Triple combinations of ARBs (olmesartan or valsartan), CCBs (amlodipine), and diuretics (hydrochlorothiazi . . .de) at any dose provided more blood pressure reduction in office and 24-hour ambulatory measurements than any dual combination of these molecules ( Daha fazlası Daha az
M.M. Bilgic | K. Yegin | T. Turkkan | M. Sengiz
Conference Object | 2012 | IEEE Antennas and Propagation Society, AP-S International Symposium (Digest) , pp.193 - 200
Aperture coupled phased array antenna design at Ku band is introduced. The array spans entire Receive Band of Ku band (10.8 GHz - 12.75 GHz) and has a gain greater than 24.5 dBi with approximately 330×70×25 mm (LxWxH) dimensions. Low loss waveguide-microstrip type hybrid feed network is also designed and simulation results are presented. Aperture efficiency greater than 70% is achieved. © 2012 IEEE.
Evranuz, EO | Arduzlar-Kagan, D
Article | 2016 | HANDBOOK OF VEGETABLE PRESERVATION AND PROCESSING, 2ND EDITION , pp.671 - 688
A Kumar | IA Ince | A Kati | R Chakraborty
Article | 2013 | INTERNATIONAL JOURNAL OF SYSTEMATIC AND EVOLUTIONARY MICROBIOLOGY63 , pp.511 - 515
A Gram-positive-staining, rod-shaped, facultatively oligotrophic bacterial strain, designated MB18(T), was isolated from a water sample collected from the River Mahananda at Siliguri (26 degrees 44' 23.20' N, 88 degrees 25' 22.89' a West-Bengal, India. On the basis of 16S rRNA gene sequence similarity, the closest relative of this strain was Brevibacterium epidermidis NCDO 2286(T) (96% similarity). The DNA G+C content of strain MB18(T) was 64.6 molo/o. Chemotaxonomic data [MK-8(H-2) as the major menaquinone, galactose as the sole cell-wall sugar, meso-diaminopimelic acid as the diagnostic cell-wall diamino acid, phosphatidylglycerol . . . and diphosphatidylglycerol as constituents of the polar lipids, anteiso-C-15:0, anteiso-C-17:0 and iso-C-15:0 as the major fatty acids] supported the affiliation of strain MB18T to the genus Brevibacterium. The results of DNA G +C content, 16S rRNA gene sequence analysis and biochemical and physiological analyses allowed genotypic and phenotypic differentiation of strain MB18(T) from its nearest neighbour B. epidermidis. The isolate therefore represents a novel species, for which the name Brevibacterium siliguriense sp. nov. is proposed; the type strain is MB18(T) (=DSM 23676(T)=LMG 25772(T)) Daha fazlası Daha az
A. Kumar | I.A. Ince | A. Kati | R. Chakraborty
Article | 2013 | International Journal of Systematic and Evolutionary Microbiology63 ( PART2 ) , pp.511 - 515
A Gram-positive-staining, rod-shaped, facultatively oligotrophic bacterial strain, designated MB18T, was isolated from a water sample collected from the River Mahananda at Siliguri (26° 44' 23.20' N, 88° 25' 22.89' E), West-Bengal, India. On the basis of 16S rRNA gene sequence similarity, the closest relative of this strain was Brevibacterium epidermidis NCDO 2286T (96% similarity). The DNA G+C content of strain MB18T was 64.6 mol%. Chemotaxonomic data [MK-8(H2) as the major menaquinone, galactose as the sole cell-wall sugar, meso-diaminopimelic acid as the diagnostic cell-wall diamino acid, phosphatidylglycerol and diphosphatidylgl . . .ycerol as constituents of the polar lipids, anteiso-C15: 0, anteiso-C17: 0 and iso-C15: 0 as the major fatty acids] supported the affiliation of strain MB18T to the genus Brevibacterium. The results of DNA G+C content, 16S rRNA gene sequence analysis and biochemical and physiological analyses allowed genotypic and phenotypic differentiation of strain MB18T from its nearest neighbour B. epidermidis. The isolate therefore represents a novel species, for which the name Brevibacterium siliguriense sp. nov. is proposed; the type strain is MB18T (=DSM 23676T=LMG 25772T). © 2013 IUMS Daha fazlası Daha az
Article | 2008 | European Journal of Social Sciences7 ( 2 ) , pp.18 - 32
Although European Union already plays a significant role in shaping international society, it may still influence international society more effectively. In this study, this claim will be demonstrated with reference to the success of European countries in transforming the concept of sovereignty and to three other characteristics of the union which have emerged in the process of integration: (1) implicit formation, (2) passive defense, and (3) will-power and concert. Moreover, it will be argued that arrangements, which remove structural inconsistencies of the union, and policies, which facilitate inclusion of Turkey to the union, wil . . .l play a significant role in enhancing the European Union's capacity to mould the international society. As a result, in spite of its inability to affect international order, this paper will describe the Union's potential to influence international society and discuss the strategies to increase this potential Daha fazlası Daha az
Özdurak, C. | Ulusoy, V.
Article | 2012 | European Journal of Economics, Finance and Administrative Sciences ( 49 ) , pp.118 - 125
The aim of this paper is to analyse the different behaviors of ISE 100 Price Index, ISE Food&Beverages Sector Index, ISE Bank Sector Index and Ülker Bisküvi stock focusing on the outperformance of ISE Food&Beverages Sector Index and Ülker Bisküvi against the markets after 2008 global financial crisis. We used GARCH models to understand the bahvior of the indices and Ülker Bisküvi stock returns before and after the global financial crisis which we concluded that the outperformance of Ülker is related with its business restructuring events and dividend payment announces rater than global indicator while indices, especially Bank Sector . . . Index, are much more related with global financial market developments. © EuroJournals, Inc. 2012 Daha fazlası Daha az
Aytekin, O. | Turgut, S. | Üstoglu Ünal, V. | Akşahin, E. | Tomak, M.
Article | 2013 | Physica E: Low-Dimensional Systems and Nanostructures54 , pp.257 - 261
A theoretical study of the effect of the confining potential on the nonlinear optical properties of two dimensional quantum dots is performed. A three-parameter Woods-Saxon potential is used within the density matrix formalism. The control of confinement by three parameters and an applied electric field gives one quite an advantage in studying their effects on the nonlinear properties. The coefficients investigated include the optical rectification, second and third-harmonic generation and the change in the refractive index. Their dependence on the electric field values, dot size and the energy of the incoming photons is studied ext . . .ensively. It is shown that the Woods-Saxon potential can be used to model the confinement in quantum dots with considerable success. © 2013 Elsevier B.V Daha fazlası Daha az
Article | 2017 | World Literature Studies9 ( 4 ) , pp.74 - 88
Çalişkan, E. | Çakiroglu, Y. | Coşkun, E. | Kumbak, B. | Müezzinoglu, B. | Çorakçi, A.
Article | 2009 | Journal of the Turkish German Gynecology Association10 ( 4 ) , pp.194 - 198
Objective: To evaluate the effect of a copper intrauterine device on the expression of mucin- 1 (MUC1) and integrin ß1 in the luteal phase endometrium. Material and Methods: 25 regularly menstruating women (25-35 years) who were willing to use copper intrauterine device contraception participated in this study. Endometrial sampling via a Pipelle canulla was performed on the 24th day of their cycle and repeated three months after insertion of TCu380A IUD. Immunohistochemical staining was performed for MUC1 and integrin ß1 in the endometrial sections. Staining intensity was graded under the conventional light microscope. Results: The . . .mean age of the study population was 32.8±5.3 years (25-35). MUC1 expression of the endometrial luminal epithelium cytoplasm and the luminal epithelium increased significantly after three months of IUD usage (p=0.01; p<0.001 respectively). Neither integrin ß1 expression of endometrial luminal epithelium cytoplasma nor of the endometrial stroma changed after three months of IUD usage (p=0.16; p=0.22 respectively). Conclusion: The increase of the embryo implantation inhibitor MUC1 synthesis may be responsible for the IUD's mechanism of action for pregnancy prevention. Integrin ß1 expression of the endometrial luminal epithelium cytoplasm and stroma are not affected by the use of copper IUD Daha fazlası Daha az